aeo.owl
type: Ontology
date: 04:07:2013 20:24
has_obo_format_version: 1.2
auto-generated-by: OBO-Edit 2.1.1-beta7
typeref: anatomical_entity_ontology
default-namespace: anatomical_entity_ontology
saved-by: jonathanbard
comment: this version corrects the namespace and includes some flybase alt_IDs
version IRI: aeo.owl

definition
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_obo_format_version
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

derives_from
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: derives_from

descends
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: descends

develops_from
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: develops_from

endStage
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: endStage

hasMapping
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: hasMapping

has_part
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: has_part

isReferenceForMapping
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: isReferenceForMapping

part_of
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: part_of

startStage
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: startStage

subEventOf
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: subEventOf

type
type: ObjectProperty
has_obo_namespace: anatomical_entity_ontology
id: type

single-cell tissue
type: Class
subclass of: simple tissue
id: AEO:0000013
definition: Anatomical structure composed of a single cell.
has_alternative_id: EHDAA2:0003013
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure composed of a single cell.
database_cross_reference: CARO:MAH
annotated source: single-cell tissue
annotated property: definition

lumen of tube
type: Class
subclass of: open anatomical space
id: AEO:0000078
has_alternative_id: EHDAA2:0003078
definition: The inner space within a tube.
has_alternative_id: UBERON:0005082
has_obo_namespace: http://www.xspan.org/obo.owl#
has_related_synonym: tube lumen

Axiom
database_cross_reference: AEO:JB
annotated target: The inner space within a tube.
annotated source: lumen of tube
annotated property: definition

lumen of epithelial sac
type: Class
subclass of: enclosed anatomical space
definition: A small cavity bounded by an epithelium.
id: AEO:0000079
has_alternative_id: EHDAA2:0003079
has_related_synonym: cavity of vesicle
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A small cavity bounded by an epithelium.
database_cross_reference: AEO:JB
annotated source: lumen of epithelial sac
annotated property: definition

foramen
type: Class
subclass of: anatomical surface
definition: A hole in a tissue.
id: AEO:0000080
has_alternative_id: EHDAA2:0003080
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A hole in a tissue.
database_cross_reference: AEO:JB
annotated source: foramen
annotated property: definition

matrix-based tissue
type: Class
subclass of: simple tissue
definition: A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified.
id: AEO:0000081
has_alternative_id: EHDAA2:0003081
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified.
database_cross_reference: AEO:JB
annotated source: matrix-based tissue
annotated property: definition

bone
type: Class
subclass of: multi-tissue structure
id: AEO:0000082
has_alternative_id: EHDAA2:0003082
definition: Ossified structure that is predominantly extracellular matrix and forms part of the support system of the body.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Ossified structure that is predominantly extracellular matrix and forms part of the support system of the body.
annotated source: bone
annotated property: definition

endochondral bone
type: Class
subclass of: bone
subclass of: Restriction
  on property: has_part
  some values from: chondrocyte
subclass of: Restriction
  on property: has_part
  some values from: chondroblast
subclass of: Restriction
  on property: has_part
  some values from: osteoblast
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
id: AEO:0000083
definition: Bone that is preformed in cartilage.
has_alternative_id: EHDAA2:0003083
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Bone that is preformed in cartilage.
database_cross_reference: VAO:0000145
annotated source: endochondral bone
annotated property: definition

membrane bone
type: Class
subclass of: bone
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
subclass of: Restriction
  on property: has_part
  some values from: osteoblast
id: AEO:0000085
definition: Bone that forms directly from mesenchyme.
has_alternative_id: EHDAA2:0003085
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Bone that forms directly from mesenchyme.
database_cross_reference: VAO:0000023
annotated source: membrane bone
annotated property: definition

sesamoid bone
type: Class
subclass of: endochondral bone
subclass of: Restriction
  on property: has_part
  some values from: chondrocyte
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
subclass of: Restriction
  on property: has_part
  some values from: chondroblast
id: AEO:0000086
definition: An endochondral bone that forms within tendenous or ligamentous matrix.
has_alternative_id: EHDAA2:0003086
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An endochondral bone that forms within tendenous or ligamentous matrix.
database_cross_reference: VAO:0000137
annotated source: sesamoid bone
annotated property: definition

cartilage
type: Class
subclass of: matrix-based tissue
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
id: AEO:0000087
definition: Dense connective tissue made primarily of type II collagen.
has_alternative_id: EHDAA2:0003087
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Dense connective tissue made primarily of type II collagen.
database_cross_reference: VAO:0000040
annotated source: cartilage
annotated property: definition

ligament
type: Class
subclass of: matrix-based tissue
subclass of: Restriction
  on property: has_part
  some values from: extracellular matrix secreting cell
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
subclass of: Restriction
  on property: has_part
  some values from: fibroblast
definition: A strap of predominantly extracellular matrix connecting two bones.
id: AEO:0000090
has_alternative_id: EHDAA2:0003090
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A strap of predominantly extracellular matrix connecting two bones.
database_cross_reference: AEO:JB
annotated source: ligament
annotated property: definition

tendon
type: Class
subclass of: matrix-based tissue
subclass of: Restriction
  on property: has_part
  some values from: extracellular matrix secreting cell
subclass of: Restriction
  on property: has_part
  some values from: fibroblast
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
definition: A strap of predominantly extracellular matrix connecting a muscle to a bone.
id: AEO:0000091
has_alternative_id: EHDAA2:0003091
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A strap of predominantly extracellular matrix connecting a muscle to a bone.
database_cross_reference: AEO:JB
annotated source: tendon
annotated property: definition

aponeurosis
type: Class
subclass of: matrix-based tissue
subclass of: Restriction
  on property: has_part
  some values from: extracellular matrix secreting cell
subclass of: Restriction
  on property: has_part
  some values from: connective tissue cell
definition: A sheet of extracellular matrix.
id: AEO:0000092
has_alternative_id: EHDAA2:0003092
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A sheet of extracellular matrix.
database_cross_reference: AEO:JB
annotated source: aponeurosis
annotated property: definition

non-connected functional system
type: Class
subclass of: anatomical cluster
id: AEO:0000093
definition: An anatomical group whose component structures share a common function.
has_alternative_id: EHDAA2:0003093
has_alternative_id: FBbt:00007278
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An anatomical group whose component structures share a common function.
annotated source: non-connected functional system
annotated property: definition

sense organ
type: Class
subclass of: compound organ
id: AEO:0000094
has_alternative_id: EHDAA2:0003094f
has_alternative_id: FBbt:00005155
definition: Multicellular anatomical structure with largely bona fide boundary that transduces some sensory stimulus to the nervous system.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Multicellular anatomical structure with largely bona fide boundary that transduces some sensory stimulus to the nervous system.
annotated source: sense organ
annotated property: definition

fluid-based anatomical entity
type: Class
subclass of: multi-tissue structure
id: AEO:0000095
has_alternative_id: EHDAA2:0003095
definition: Fluid anatomical entity containing cells.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Fluid anatomical entity containing cells.
annotated source: fluid-based anatomical entity
annotated property: definition

gland
type: Class
subclass of: multi-tissue structure
definition: A multi-tissue structure that produces a secretion for use elsewhere in the body.
id: AEO:0000096
has_alternative_id: EHDAA2:0003096
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A multi-tissue structure that produces a secretion for use elsewhere in the body.
database_cross_reference: AEO:JB
annotated source: gland
annotated property: definition

ducted gland
type: Class
subclass of: gland
definition: A gland that releases its secretion through a duct.
id: AEO:0000097
has_alternative_id: EHDAA2:0003097
has_related_synonym: exocrine gland.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A gland that releases its secretion through a duct.
database_cross_reference: AEO:JB
annotated source: ducted gland
annotated property: definition

ductless gland
type: Class
subclass of: gland
definition: A gland that releases its secretion directly into the bloodstream, or equivalent for an invertebrate.
id: AEO:0000098
has_alternative_id: EHDAA2:0003098
has_related_synonym: endocrine gland.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A gland that releases its secretion directly into the bloodstream, or equivalent for an invertebrate.
database_cross_reference: AEO:JB
annotated source: ductless gland
annotated property: definition

Axiom
database_cross_reference: AEO:JB
annotated target: endocrine gland.
annotated source: ductless gland
annotated property: has_related_synonym

keratin-based structure
type: Class
subclass of: acellular anatomical structure
id: AEO:0000099
definition: Acellular anatomical structure whose predominant constituent is keratin.
has_alternative_id: EHDAA2:0003099
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Acellular anatomical structure whose predominant constituent is keratin.
annotated source: keratin-based structure
annotated property: definition

chitin-based structure
type: Class
subclass of: acellular anatomical structure
id: AEO:0000100
definition: Acellular anatomical structure whose predominant constituent is chitin.
has_alternative_id: EHDAA2:0003100
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Acellular anatomical structure whose predominant constituent is chitin.
annotated source: chitin-based structure
annotated property: definition

body
type: Class
subclass of: organism subdivision
id: AEO:0000103
has_alternative_id: EHDAA2:0003103
definition: The region of the organism associated with the visceral organs.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The region of the organism associated with the visceral organs.
annotated source: body
annotated property: definition

head
type: Class
subclass of: organism subdivision
id: AEO:0000106
has_alternative_id: EHDAA2:0003106
definition: The region of the body containing the brain and mouth.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The region of the body containing the brain and mouth.
annotated source: head
annotated property: definition

neck
type: Class
subclass of: organism subdivision
id: AEO:0000108
has_alternative_id: EHDAA2:0003108
definition: The region of the body connecting the head and the body.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The region of the body connecting the head and the body.
annotated source: neck
annotated property: definition

tail
type: Class
subclass of: appendage
id: AEO:0000109
definition: An external caudal extension of the body.
has_alternative_id: EHDAA2:0003109
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An external caudal extension of the body.
annotated source: tail
annotated property: definition

mesothelium
type: Class
subclass of: simple squamous epithelium
id: AEO:0000111
has_alternative_id: EHDAA2:0003111
definition: Epithelium derived from mesenchyme.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Epithelium derived from mesenchyme.
annotated source: mesothelium
annotated property: definition

epithelial tube
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: has_part
  some values from: duct epithelial cell
id: AEO:0000114
definition: An epithelial structure capable of allowing fluid flow.
has_alternative_id: EHDAA2:0003114
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An epithelial structure capable of allowing fluid flow.
annotated source: epithelial tube
annotated property: definition

epithelial sac
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: has_part
  some values from: columnar/cuboidal epithelial cell
id: AEO:0000115
definition: An epithelial pouch with a single opening.
has_alternative_id: EHDAA2:0003115
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An epithelial pouch with a single opening.
annotated source: epithelial sac
annotated property: definition

arborising epithelial duct system
type: Class
subclass of: epithelial sac
subclass of: Restriction
  on property: has_part
  some values from: duct epithelial cell
definition: A group of connected epithelial tubes with a single portal.
id: AEO:0000117
has_alternative_id: EHDAA2:0003117
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A group of connected epithelial tubes with a single portal.
database_cross_reference: AEO:JB
annotated source: arborising epithelial duct system
annotated property: definition

epithelial plexus
type: Class
subclass of: epithelial tube
subclass of: Restriction
  on property: has_part
  some values from: duct epithelial cell
definition: A network of interlinking epithelial tubes.
id: AEO:0000118
has_alternative_id: EHDAA2:0003118
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A network of interlinking epithelial tubes.
database_cross_reference: AEO:JB
annotated source: epithelial plexus
annotated property: definition

epithelial vesicle
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: has_part
  some values from: columnar/cuboidal epithelial cell
definition: A closed epithelium with a lumen.
id: AEO:0000119f
has_alternative_id: EHDAA2:0003119
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A closed epithelium with a lumen.
database_cross_reference: AEO:JB
annotated source: epithelial vesicle
annotated property: definition

muscle tissue
type: Class
subclass of: simple tissue
definition: A tissue composed of myoblasts or muscle cells.
id: AEO:0000122
has_alternative_id: EHDAA2:0003122
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A tissue composed of myoblasts or muscle cells.
database_cross_reference: AEO:JB
annotated source: muscle tissue
annotated property: definition

neural tissue
type: Class
subclass of: simple tissue
id: AEO:0000123
has_alternative_id: EHDAA2:0003123
definition: Tissue composed predominantly of neurons.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Tissue composed predominantly of neurons.
annotated source: neural tissue
annotated property: definition

developing anatomical structure
type: Class
subclass of: anatomical structure
definition: A structure whose morphology or state of differentiation will change during normal development.
id: AEO:0000125
has_alternative_id: EHDAA2:0003125
has_alternative_id: UBERON:0005423
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A structure whose morphology or state of differentiation will change during normal development.
database_cross_reference: AEO:JB
annotated source: developing anatomical structure
annotated property: definition

larva
type: Class
subclass of: multi-cellular organism
definition: A post-embryonic juvenile form which will undergo metamorphosis to become the adult.
id: AEO:0000126
has_alternative_id: EHDAA2:0003126
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A post-embryonic juvenile form which will undergo metamorphosis to become the adult.
database_cross_reference: AEO:JB
annotated source: larva
annotated property: definition

apoptosing developing anatomical entity
type: Class
subclass of: developing anatomical structure
subclass of: Restriction
  on property: has_part
  some values from: apoptosis fated cell
id: AEO:0000127
definition: An embryonic anatomical structure undergoing apoptosis.
has_alternative_id: EHDAA2:0003127
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An embryonic anatomical structure undergoing apoptosis.
annotated source: apoptosing developing anatomical entity
annotated property: definition

functioning and developing structure
type: Class
subclass of: developing anatomical structure
id: AEO:0000129
definition: An embryonic entity that displays a physiological function but whose strucuture is not yet fully formed.
has_alternative_id: EHDAA2:0003129
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An embryonic entity that displays a physiological function but whose strucuture is not yet fully formed.
annotated source: functioning and developing structure
annotated property: definition

developing structure with stem cells
type: Class
subclass of: developing anatomical structure
subclass of: Restriction
  on property: has_part
  some values from: stem cell
id: AEO:0000131
has_alternative_id: EHDAA2:0003131
definition: Embronic structure that contains stem cellsr that may contribute to its future development or maintenance or to its future development or maintenance of another tissue.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Embronic structure that contains stem cellsr that may contribute to its future development or maintenance or to its future development or maintenance of another tissue.
annotated source: developing structure with stem cells
annotated property: definition

transitional anatomical structure
type: Class
subclass of: developing anatomical structure
id: AEO:0000132
definition: An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development.
has_alternative_id: EHDAA2:0003132
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development.
annotated source: transitional anatomical structure
annotated property: definition

ganglion
type: Class
subclass of: neural tissue
definition: A group of neurons, usually outside the CNS, which relay neuronal signals.
id: AEO:0000135
has_alternative_id: EHDAA2:0003135
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A group of neurons, usually outside the CNS, which relay neuronal signals.
database_cross_reference: AEO:JB
annotated source: ganglion
annotated property: definition

neuronal nucleus
type: Class
subclass of: neuronal grey matter
subclass of: Restriction
  on property: has_part
  some values from: astrocyte
subclass of: Restriction
  on property: has_part
  some values from: microglial cell
subclass of: Restriction
  on property: has_part
  some values from: oligodendrocyte
definition: A localised domain of predominantly neuronal tissue in the central nervous system.
id: AEO:0000136
has_alternative_id: EHDAA2:0003136
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A localised domain of predominantly neuronal tissue in the central nervous system.
database_cross_reference: AEO:JB
annotated source: neuronal nucleus
annotated property: definition

nerve
type: Class
subclass of: neural tissue
definition: A group of neurons that provides a nervous supply.
id: AEO:0000137
has_alternative_id: EHDAA2:0003137
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A group of neurons that provides a nervous supply.
database_cross_reference: AEO:JB
annotated source: nerve
annotated property: definition

nerve plexus
type: Class
subclass of: neural tissue
subclass of: Restriction
  on property: has_part
  some values from: afferent neuron
subclass of: Restriction
  on property: has_part
  some values from: efferent neuron
definition: A complex of interconnecting nerves.
id: AEO:0000138
has_alternative_id: EHDAA2:0003138
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A complex of interconnecting nerves.
database_cross_reference: AEO:JB
annotated source: nerve plexus
annotated property: definition

nerve fiber tract
type: Class
subclass of: neuronal white matter
definition: A fasciculated bundle of neuron projections, largely or completely lacking synapses.
id: AEO:0000139
has_alternative_id: EHDAA2:0003139
has_obo_namespace: http://www.xspan.org/obo.owl#
has_related_synonym: neuron projection bundle

Axiom
database_cross_reference: GO:0043005
annotated target: neuron projection bundle
annotated source: nerve fiber tract
annotated property: has_related_synonym

Axiom
annotated target: A fasciculated bundle of neuron projections, largely or completely lacking synapses.
database_cross_reference: CARO:0001001
database_cross_reference: GO:0043005
annotated source: nerve fiber tract
annotated property: definition

striated muscle tissue
type: Class
subclass of: muscle tissue
subclass of: Restriction
  on property: has_part
  some values from: striated muscle cell
definition: A tissue composed of striated muscle cells.
id: AEO:0000140
has_alternative_id: EHDAA2:0003140
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A tissue composed of striated muscle cells.
database_cross_reference: AEO:JB
annotated source: striated muscle tissue
annotated property: definition

smooth muscle tissue
type: Class
subclass of: muscle tissue
subclass of: Restriction
  on property: has_part
  some values from: smooth muscle cell
definition: A tissue composed of smooth muscle cells.
id: AEO:0000141
has_alternative_id: EHDAA2:0003141
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A tissue composed of smooth muscle cells.
database_cross_reference: AEO:JB
annotated source: smooth muscle tissue
annotated property: definition

cardiac muscle tissue
type: Class
subclass of: muscle tissue
subclass of: Restriction
  on property: has_part
  some values from: cardiac muscle cell
definition: A tissue composed of cardiac muscle cells.
id: AEO:0000142
has_alternative_id: EHDAA2:0003142
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A tissue composed of cardiac muscle cells.
database_cross_reference: AEO:JB
annotated source: cardiac muscle tissue
annotated property: definition

smooth muscle sphincter
type: Class
subclass of: smooth muscle tissue
subclass of: Restriction
  on property: has_part
  some values from: smooth muscle cell
definition: A ring of smooth muscle cells whose contraction closes the opening of the ring.
id: AEO:0000143
has_alternative_id: EHDAA2:0003143
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A ring of smooth muscle cells whose contraction closes the opening of the ring.
database_cross_reference: AEO:JB
annotated source: smooth muscle sphincter
annotated property: definition

striated muscle sphincter
type: Class
subclass of: striated muscle tissue
subclass of: Restriction
  on property: has_part
  some values from: striated muscle cell
definition: A ring of striated muscle cells whose contraction closes the opening of the ring.
id: AEO:0000144
has_alternative_id: EHDAA2:0003144
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A ring of striated muscle cells whose contraction closes the opening of the ring.
database_cross_reference: AEO:JB
annotated source: striated muscle sphincter
annotated property: definition

mesenchymal tissue
type: Class
subclass of: simple tissue
definition: A group of not-yet-terminally-differentiatied cells that can pack in three dimensions.
id: AEO:0000145
has_alternative_id: EHDAA2:0003145
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A group of not-yet-terminally-differentiatied cells that can pack in three dimensions.
database_cross_reference: AEO:JB
annotated source: mesenchymal tissue
annotated property: definition

dense mesenchyme tissue
type: Class
subclass of: mesenchymal tissue
subclass of: Restriction
  on property: has_part
  some values from: fibroblast
id: AEO:0000146
has_alternative_id: EHDAA2:0003146
definition: Mesenchyme with little extracellular matrix.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Mesenchyme with little extracellular matrix.
annotated source: dense mesenchyme tissue
annotated property: definition

cartilagenous condensation
type: Class
subclass of: developing mesenchymal condensation
subclass of: Restriction
  on property: has_part
  some values from: chondroblast
id: AEO:0000147
definition: Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes.
has_alternative_id: EHDAA2:0003147
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes.
database_cross_reference: GO:curator
database_cross_reference: VAO:0000092
annotated source: cartilagenous condensation
annotated property: definition

developing mesenchymal condensation
type: Class
subclass of: dense mesenchyme tissue
subclass of: developing mesenchymal structure
subclass of: Restriction
  on property: has_part
  some values from: mesenchyme condensation cell
definition: A delimited region of dense mesenchyme within looser mesenchyme.
id: AEO:0000148
has_alternative_id: EHDAA2:0003148
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A delimited region of dense mesenchyme within looser mesenchyme.
database_cross_reference: AEO:JB
annotated source: developing mesenchymal condensation
annotated property: definition

pre-muscle condensation
type: Class
subclass of: developing mesenchymal condensation
subclass of: Restriction
  on property: has_part
  some values from: muscle precursor cell
definition: A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become myoblasts.
id: AEO:0000149
has_alternative_id: EHDAA2:0003149
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become myoblasts.
database_cross_reference: AEO:JB
annotated source: pre-muscle condensation
annotated property: definition

pre-cartilage condensation
type: Class
subclass of: developing mesenchymal condensation
subclass of: Restriction
  on property: has_part
  some values from: mesenchyme condensation cell
definition: A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts.
id: AEO:0000150
has_alternative_id: EHDAA2:0003150
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts.
database_cross_reference: AEO:JB
annotated source: pre-cartilage condensation
annotated property: definition

loose mesenchyme tissue
type: Class
subclass of: mesenchymal tissue
subclass of: Restriction
  on property: has_part
  some values from: extracellular matrix secreting cell
subclass of: Restriction
  on property: has_part
  some values from: fibroblast
id: AEO:0000151
has_alternative_id: EHDAA2:0003151
definition: Mesenchyme whose cells are embedded in obvious amounts fo extracellular matrix.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Mesenchyme whose cells are embedded in obvious amounts fo extracellular matrix.
annotated source: loose mesenchyme tissue
annotated property: definition

migrating mesenchyme population
type: Class
subclass of: mesenchymal tissue
subclass of: Restriction
  on property: has_part
  some values from: mesenchymal cell
id: AEO:0000152
has_alternative_id: EHDAA2:0003152
definition: Mesenchymal cells that are migrating.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Mesenchymal cells that are migrating.
annotated source: migrating mesenchyme population
annotated property: definition

mesenchymal tissue with stem cells
type: Class
subclass of: multi-tissue structure with stem cells
id: AEO:0000153
has_alternative_id: EHDAA2:0003153
definition: Multi-tissue mesenchymal structure one of whose parts contains stem cells that can replace other parts.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Multi-tissue mesenchymal structure one of whose parts contains stem cells that can replace other parts.
annotated source: mesenchymal tissue with stem cells
annotated property: definition

organism surfacef
type: Class
subclass of: organism subdivision
id: AEO:0000154
has_alternative_id: EHDAA2:0003154
definition: The collection of structures that form the exxtenal covering of the organism.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The collection of structures that form the exxtenal covering of the organism.
annotated source: organism surfacef
annotated property: definition

groove
type: Class
subclass of: anatomical surface
definition: A furrow or an incomplete tube.
id: AEO:0000161
has_alternative_id: EHDAA2:0003161
has_alternative_id: UBERON:0006846
has_alternative_id: ZFA:0001690
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A furrow or an incomplete tube.
database_cross_reference: AEO:JB
annotated source: groove
annotated property: definition

ridge
type: Class
subclass of: anatomical surface
definition: A raised strip of tissue.
id: AEO:0000162
has_alternative_id: EHDAA2:0003162
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A raised strip of tissue.
database_cross_reference: AEO:JB
annotated source: ridge
annotated property: definition

skeletal system
type: Class
subclass of: anatomical system
id: AEO:0000168
has_alternative_id: EHDAA2:0003168
definition: The rigid support system for the body.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The rigid support system for the body.
database_cross_reference: VAO:0000027
annotated source: skeletal system
annotated property: definition

embryo
type: Class
subclass of: multi-cellular organism
subclass of: Restriction
  on property: part_of
  some values from: conceptus
id: AEO:0000169
has_alternative_id: EHDAA2:0003169
definition: That part of the conceptus that will form the organism.
has_alternative_id: UBERON:0000922
has_alternative_id: ZFA:0001105
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: That part of the conceptus that will form the organism.
annotated source: embryo
annotated property: definition

anlage
type: Class
subclass of: developing anatomical structure
id: AEO:0000170
definition: Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue.
has_alternative_id: EHDAA2:0003170
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue.
annotated source: anlage
annotated property: definition

primordium
type: Class
subclass of: developing anatomical structure
id: AEO:0000171
has_alternative_id: EHDAA2:0003171
definition: Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue.
annotated source: primordium
annotated property: definition

limb
type: Class
subclass of: appendage
id: AEO:0000172
definition: Appendage of an animal used for locomotion or grasping.
has_alternative_id: EHDAA2:0003172
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Appendage of an animal used for locomotion or grasping.
annotated source: limb
annotated property: definition

surface sense organ
type: Class
subclass of: sense organ
subclass of: Restriction
  on property: part_of
  some values from: organism surfacef
id: AEO:0000173
has_alternative_id: EHDAA2:0003173
definition: Multicellular anatomical structure with largely bona fide boundary that extends outwards from or is part of the organism surface and transduces some sensory stimulus to the nervous system.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Multicellular anatomical structure with largely bona fide boundary that extends outwards from or is part of the organism surface and transduces some sensory stimulus to the nervous system.
annotated source: surface sense organ
annotated property: definition

gender-specific anatomical structure
type: Class
subclass of: anatomical structure
definition: A part of the body present only in a specific gender.
id: AEO:0000174
has_alternative_id: EHDAA2:0003174
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A part of the body present only in a specific gender.
database_cross_reference: AEO:JB
annotated source: gender-specific anatomical structure
annotated property: definition

male anatomical structure
type: Class
subclass of: gender-specific anatomical structure
definition: A part of the body present only in males.
id: AEO:0000175
has_alternative_id: EHDAA2:0003175
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A part of the body present only in males.
database_cross_reference: AEO:JB
annotated source: male anatomical structure
annotated property: definition

female anatomical structure
type: Class
subclass of: gender-specific anatomical structure
definition: A part of the body present only in females.
id: AEO:0000176
has_alternative_id: EHDAA2:0003176
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A part of the body present only in females.
database_cross_reference: AEO:JB
annotated source: female anatomical structure
annotated property: definition

hermaphrodite anatomical structure
type: Class
subclass of: gender-specific anatomical structure
definition: A part of the body present only in hermaphrodites.
id: AEO:0000177
has_alternative_id: EHDAA2:0003177
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A part of the body present only in hermaphrodites.
database_cross_reference: AEO:JB
annotated source: hermaphrodite anatomical structure
annotated property: definition

fibrous joint
type: Class
subclass of: matrix-based tissue
subclass of: Restriction
  on property: has_part
  some values from: connective tissue cell
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
definition: A flexible joint between two bones that is made of unossified connective tissue.
id: AEO:0000178
has_alternative_id: EHDAA2:0003178
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A flexible joint between two bones that is made of unossified connective tissue.
database_cross_reference: AEO:JB
annotated source: fibrous joint
annotated property: definition

joint-associated cartilage
type: Class
subclass of: cartilage
subclass of: Restriction
  on property: part_of
  some values from: endochondral bone
subclass of: Restriction
  on property: has_part
  some values from: chondrocyte
subclass of: Restriction
  on property: part_of
  some values from: synovial joint
subclass of: Restriction
  on property: has_part
  some values from: chondroblast
id: AEO:0000179
has_alternative_id: EHDAA2:0003179
definition: The articular cartilage covering of the region of bone within a synoval joint.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The articular cartilage covering of the region of bone within a synoval joint.
annotated source: joint-associated cartilage
annotated property: definition

non-joint-associated cartilage
type: Class
subclass of: cartilage
subclass of: Restriction
  on property: has_part
  some values from: chondroblast
subclass of: Restriction
  on property: has_part
  some values from: chondrocyte
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
id: AEO:0000180
definition: Cartilage that may provide the template for an endochondral bone or that may be a disinct entity in the skeleton.
has_alternative_id: EHDAA2:0003180
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Cartilage that may provide the template for an endochondral bone or that may be a disinct entity in the skeleton.
annotated source: non-joint-associated cartilage
annotated property: definition

synovial membrane
type: Class
subclass of: multilaminar epithelium
subclass of: Restriction
  on property: part_of
  some values from: synovial joint
subclass of: Restriction
  on property: has_part
  some values from: stratified epithelial cell
id: AEO:0000181
has_alternative_id: EHDAA2:0003181
definition: The epithelial membrane between bone ends that forms the lateral borders of the synovial cavity and secretes synovial fluid.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The epithelial membrane between bone ends that forms the lateral borders of the synovial cavity and secretes synovial fluid.
annotated source: synovial membrane
annotated property: definition

synovial joint
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
definition: A joint connecting two or more bones with cartilage at the bone ends and a synovial membrane that secretes synovial fluid conecting the bones and sealing the synovial cavity.
id: AEO:0000183
has_alternative_id: EHDAA2:0003183
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A joint connecting two or more bones with cartilage at the bone ends and a synovial membrane that secretes synovial fluid conecting the bones and sealing the synovial cavity.
database_cross_reference: AEO:JB
annotated source: synovial joint
annotated property: definition

exoskeletal tissue
type: Class
subclass of: matrix-based tissue
subclass of: Restriction
  on property: part_of
  some values from: skeletal system
subclass of: Restriction
  on property: has_part
  some values from: cuticle secreting cell
definition: A component of the exoskeleton.
id: AEO:0000185
has_alternative_id: EHDAA2:0003185
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A component of the exoskeleton.
database_cross_reference: AEO:JB
annotated source: exoskeletal tissue
annotated property: definition

body cavity
type: Class
subclass of: anatomical space
id: AEO:0000186
has_alternative_id: EHDAA2:0003186
definition: The cavity within the body that contains the visceral organs.
has_alternative_id: UBERON:0002323
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The cavity within the body that contains the visceral organs.
annotated source: body cavity
annotated property: definition

multi-tissue structure with stem cells
type: Class
subclass of: multi-tissue structure
id: AEO:0000187
has_alternative_id: EHDAA2:0003187
definition: Multi-tissue structure one of whose parts contains stem cells that can replace other parts.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Multi-tissue structure one of whose parts contains stem cells that can replace other parts.
annotated source: multi-tissue structure with stem cells
annotated property: definition

acellular fluid anatomical entity
type: Class
subclass of: acellular anatomical structure
id: AEO:0000188
definition: An acellular fluid portion of organism substance that is produced by the organism for some non-waste purpose.
has_alternative_id: EHDAA2:0003188
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An acellular fluid portion of organism substance that is produced by the organism for some non-waste purpose.
annotated source: acellular fluid anatomical entity
annotated property: definition

epithelial tissue with stem cells
type: Class
subclass of: multi-tissue structure with stem cells
id: AEO:0000189
has_alternative_id: EHDAA2:0003189
definition: Multi-tissue epithelial structure one of whose parts contains stem cells that can replace other parts.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Multi-tissue epithelial structure one of whose parts contains stem cells that can replace other parts.
annotated source: epithelial tissue with stem cells
annotated property: definition

anatomical surface feature
type: Class
id: AEO:0000192
has_alternative_id: EHDAA2:0003010
definition: Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures.
has_related_synonym: anatomical surface.
has_obo_namespace: http://www.xspan.org/obo.owl#
deprecated: true

Axiom
database_cross_reference: CARO:MAH
annotated target: Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures.
annotated source: anatomical surface feature
annotated property: definition

appendage
type: Class
subclass of: organism subdivision
id: AEO:0000193
has_alternative_id: EHDAA2:0003193
definition: Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified]. An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs.
has_alternative_id: UBERON:0000026
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified]. An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs.
annotated source: appendage
annotated property: definition

conceptus
type: Class
subclass of: multi-cellular organism
id: AEO:0000194
definition: All the products of the fertilized egg.
has_alternative_id: EHDAA2:0003205
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: All the products of the fertilized egg.
annotated source: conceptus
annotated property: definition

extraembryonic component
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part_of
  some values from: conceptus
id: AEO:0000195
definition: The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism.
annotated source: extraembryonic component
annotated property: definition

larval anatomical structure
type: Class
subclass of: developing anatomical structure
subclass of: Restriction
  on property: part_of
  some values from: larva
id: AEO:0000196
definition: An anatomical structure present in the larval form of an animal.
has_alternative_id: HDAA2:0003126
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An anatomical structure present in the larval form of an animal.
annotated source: larval anatomical structure
annotated property: definition

antenna
type: Class
subclass of: surface sense organ
subclass of: Restriction
  on property: part_of
  some values from: head
subclass of: Restriction
  on property: part_of
  some values from: organism surfacef
definition: A head-associated surface sense organ.
id: AEO:0000198
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A head-associated surface sense organ.
database_cross_reference: CARO:MAH
annotated source: antenna
annotated property: definition

mucous membrane
type: Class
subclass of: multi-tissue structure
definition: A membranous structure with more than one cell type, one or more of which secretes mucus, that lines body passages which communicate with the exterior.
id: AEO:0000199
has_alternative_id: EHDAA2:0003234
has_obo_namespace: http://www.xspan.org/obo.owl#
has_related_synonym: mucosa

Axiom
annotated target: A membranous structure with more than one cell type, one or more of which secretes mucus, that lines body passages which communicate with the exterior.
database_cross_reference: AEO:JB
annotated source: mucous membrane
annotated property: definition

regenerating anatomical structure
type: Class
subclass of: anatomical structure
id: AEO:0000200
definition: An anatomical structure that, as part of its normal physiology, undergoes regeneration. Examples include endometrium and antlers.
has_alternative_id: EHDAA2:0003233
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An anatomical structure that, as part of its normal physiology, undergoes regeneration. Examples include endometrium and antlers.
annotated source: regenerating anatomical structure
annotated property: definition

afferent nerve
type: Class
subclass of: nerve
subclass of: Restriction
  on property: has_part
  some values from: afferent neuron
definition: A group of neurons that provides a nervous response from a tissue.
id: AEO:0000201
has_alternative_id: EHDAA2:0003200
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A group of neurons that provides a nervous response from a tissue.
database_cross_reference: AEO:JB
annotated source: afferent nerve
annotated property: definition

efferent nerve
type: Class
subclass of: nerve
subclass of: Restriction
  on property: has_part
  some values from: efferent neuron
definition: A group of neurons that provides a nervous signal to a tissue.
id: AEO:0000202
has_alternative_id: EHDAA2:0003231
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A group of neurons that provides a nervous signal to a tissue.
database_cross_reference: AEO:JB
annotated source: efferent nerve
annotated property: definition

syncytium
type: Class
subclass of: simple tissue
subclass of: Restriction
  on property: has_part
  some values from: multinucleate cell
id: AEO:0000203
definition: An anatomical entity consisting of a single or a few multinucleated structures.
has_alternative_id: HDAA2:0003248
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO.:JB
annotated target: An anatomical entity consisting of a single or a few multinucleated structures.
annotated source: syncytium
annotated property: definition

pit
type: Class
subclass of: anatomical surface
id: AEO:0000204
definition: An roughly circular indentation in a surface.
has_alternative_id: EHDAA2:003249
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An roughly circular indentation in a surface.
annotated source: pit
annotated property: definition

protuberance
type: Class
subclass of: anatomical surface
definition: A roughly circular bulge in a surface.
id: AEO:0000205
has_alternative_id: EHDAA2:0003250
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A roughly circular bulge in a surface.
database_cross_reference: AEO:JB
annotated source: protuberance
annotated property: definition

migrating epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: has_part
  some values from: epithelial cell
id: AEO:0000206
definition: An epithelium that extends its surface area by peripheral movement.
has_alternative_id: EHDAA2:0003251
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An epithelium that extends its surface area by peripheral movement.
annotated source: migrating epithelium
annotated property: definition

blood vessel
type: Class
subclass of: epithelial tube
subclass of: Restriction
  on property: has_part
  some values from: blood vessel endothelial cell
id: AEO:0000207
definition: An epithelial tube that transports blood.
has_alternative_id: EHDAA2:0003252
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An epithelial tube that transports blood.
annotated source: blood vessel
annotated property: definition

artery
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: has_part
  some values from: blood vessel endothelial cell
id: AEO:0000208
definition: An epithelial tube that transports blood away from the heart.
has_alternative_id: EHDAA2:0003253
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An epithelial tube that transports blood away from the heart.
annotated source: artery
annotated property: definition

vein
type: Class
subclass of: blood vessel
subclass of: Restriction
  on property: has_part
  some values from: blood vessel endothelial cell
id: AEO:0000209
definition: An epithelial tube that transports blood towards the heart.
has_alternative_id: EHDAA2:0003254
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An epithelial tube that transports blood towards the heart.
annotated source: vein
annotated property: definition

row
type: Class
subclass of: anatomical group
id: AEO:0000210
definition: Anatomical group whose component structures are arranged in a row.
has_alternative_id: FBbt:00100152
has_alternative_id: HDAA2:0003255
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical group whose component structures are arranged in a row.
database_cross_reference: DBft:DOS
annotated source: row
annotated property: definition

non-connected developing functional system
type: Class
subclass of: developing anatomical structure
subclass of: anatomical cluster
id: AEO:0000211
has_alternative_id: FBbt:0004003
has_alternative_id: HDAA2:0003256
definition: The sum of all the anlagen and primordia that will develop into a single functional system.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: FBbt:DOS
annotated target: The sum of all the anlagen and primordia that will develop into a single functional system.
annotated source: non-connected developing functional system
annotated property: definition

sclerotome
type: Class
subclass of: migrating mesenchyme population
subclass of: developing mesenchymal structure
subclass of: Restriction
  on property: has_part
  some values from: mesenchymal cell
id: AEO:0000212
has_alternative_id: EHDAA2:0003257
definition: The mesenchymal derivative of a somite that will migrate to surround the neural tube and form vertebrae.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The mesenchymal derivative of a somite that will migrate to surround the neural tube and form vertebrae.
annotated source: sclerotome
annotated property: definition

bone condensation
type: Class
subclass of: developing mesenchymal condensation
subclass of: Restriction
  on property: has_part
  some values from: osteoblast
definition: A delimited region of osteoblasts representing the early stages of bone formation.
id: AEO:0000213
has_alternative_id: EHDAA2:0003258
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A delimited region of osteoblasts representing the early stages of bone formation.
database_cross_reference: AEO:JB
annotated source: bone condensation
annotated property: definition

dermomyotome
type: Class
subclass of: transitional anatomical structure
subclass of: multilaminar epithelium
subclass of: Restriction
  on property: has_part
  some values from: columnar/cuboidal epithelial cell
id: AEO:0000214
has_alternative_id: EHDAA2:0003259
definition: The bilaminar epithelium formed from the myotome and dermatome.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: The bilaminar epithelium formed from the myotome and dermatome.
annotated source: dermomyotome
annotated property: definition

open cavity
type: Class
subclass of: open anatomical space
definition: A volume that is mainly bounded but has an opening to another cavity or to the outside.
id: AEO:0000215
has_alternative_id: EHDAA2:0003078
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A volume that is mainly bounded but has an opening to another cavity or to the outside.
database_cross_reference: JB:AEO
annotated source: open cavity
annotated property: definition

epithelial cord
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: has_part
  some values from: stratified epithelial cell
definition: A cord of epithelial cells without a lumen and usually several cells thick.
id: AEO:0000216
has_alternative_id: EHDAA2:0004052
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A cord of epithelial cells without a lumen and usually several cells thick.
database_cross_reference: JB:AEO
annotated source: epithelial cord
annotated property: definition

migrating developing tissue
type: Class
subclass of: developing anatomical structure
definition: A simple coherent tissue or a localized population of similar cells that are actively migrating.
id: AEO:0000217
has_alternative_id: EHDAA2:0004053
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A simple coherent tissue or a localized population of similar cells that are actively migrating.
database_cross_reference: JB:AEO
annotated source: migrating developing tissue
annotated property: definition

developing epithelial placode
type: Class
subclass of: developing epithelium
subclass of: Restriction
  on property: has_part
  some values from: columnar/cuboidal epithelial cell
definition: A domain of columnar epithelium in an embryo that represents the early stage of the development of the epithelial component of a new anatomical structure.
id: AEO:0000218
has_alternative_id: EHDAA2:0003112
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A domain of columnar epithelium in an embryo that represents the early stage of the development of the epithelial component of a new anatomical structure.
database_cross_reference: JB:AEO
annotated source: developing epithelial placode
annotated property: definition

vascular plexus
type: Class
subclass of: epithelial plexus
subclass of: Restriction
  on property: has_part
  some values from: blood vessel endothelial cell
definition: A network of interlinked veins.
id: AEO:0000219
has_alternative_id: EHDAA2:0004112
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A network of interlinked veins.
database_cross_reference: JB:AEO
annotated source: vascular plexus
annotated property: definition

tooth
type: Class
subclass of: multi-tissue structure
id: AEO:0000220
has_alternative_id: EHDAA2:0004605
definition: Each of a set of hard, bony enamel-coated structures in the jaws of most vertebrates, used for biting and chewing.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Each of a set of hard, bony enamel-coated structures in the jaws of most vertebrates, used for biting and chewing.
database_cross_reference: JB:AEO
annotated source: tooth
annotated property: definition

open anatomical space
type: Class
subclass of: anatomical space
id: AEO:0000221
definition: An anatomical space with at least one opening to another space or the exterior.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: An anatomical space with at least one opening to another space or the exterior.
database_cross_reference: JB:AEO
annotated source: open anatomical space
annotated property: definition

enclosed anatomical space
type: Class
subclass of: anatomical space
id: AEO:0000222
definition: An anatomical space with no opening to another space or to the exterior.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: An anatomical space with no opening to another space or to the exterior.
database_cross_reference: JB:AEO
annotated source: enclosed anatomical space
annotated property: definition

fat tissue
type: Class
subclass of: simple tissue
subclass of: Restriction
  on property: has_part
  some values from: fat cell
id: AEO:0000493
has_alternative_id: EHDAA2:0003120
definition: Tissue that is predominantly made of fat cells.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Tissue that is predominantly made of fat cells.
annotated source: fat tissue
annotated property: definition

sensory ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: has_part
  some values from: Schwann cell
subclass of: Restriction
  on property: has_part
  some values from: glial cell (sensu Vertebrata)
subclass of: Restriction
  on property: has_part
  some values from: sensory neuron
definition: A ganglion containing sensory neurons.
id: AEO:0001000
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A ganglion containing sensory neurons.
database_cross_reference: JB:AEO
annotated source: sensory ganglion
annotated property: definition

autonomic ganglion
type: Class
subclass of: ganglion
subclass of: Restriction
  on property: has_part
  some values from: autonomic neuron
subclass of: Restriction
  on property: has_part
  some values from: Schwann cell
subclass of: Restriction
  on property: has_part
  some values from: efferent neuron
subclass of: Restriction
  on property: has_part
  some values from: glial cell (sensu Vertebrata)
subclass of: Restriction
  on property: has_part
  some values from: afferent neuron
definition: A ganglion that is part of the autonomic nervous system.
id: AEO:0001001
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A ganglion that is part of the autonomic nervous system.
database_cross_reference: JB:AEO
annotated source: autonomic ganglion
annotated property: definition

capillary bed
type: Class
subclass of: epithelial plexus
definition: A localized group of blood capillaries.
id: AEO:0001002
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A localized group of blood capillaries.
database_cross_reference: JB:AEO
annotated source: capillary bed
annotated property: definition

acellular extracellular matrix
type: Class
subclass of: acellular anatomical structure
id: AEO:0001003
definition: An acellular structure typically composed of collagen, glycoproteins and glycosaminoglycans.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: An acellular structure typically composed of collagen, glycoproteins and glycosaminoglycans.
database_cross_reference: JB:AEO
annotated source: acellular extracellular matrix
annotated property: definition

fin
type: Class
subclass of: appendage
definition: A flattened appendage on a marine animal.
id: AEO:0001004
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A flattened appendage on a marine animal.
database_cross_reference: JB:AEO
database_cross_reference: VAO:0000099
annotated source: fin
annotated property: definition

secretion
type: Class
subclass of: non-tissue substance
definition: A non-cellular substance released by a cell, gland or tissue.
id: AEO:0001005
has_alternative_id: UBERON:0000456
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A non-cellular substance released by a cell, gland or tissue.
database_cross_reference: JB:AEO
annotated source: secretion
annotated property: definition

excreta
type: Class
subclass of: non-tissue substance
id: AEO:0001006
definition: Excreta are bodily fluids consisting of waste matter, such as sweat or feces, discharged from the body.
has_alternative_id: UBERON:0000174
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Excreta are bodily fluids consisting of waste matter, such as sweat or feces, discharged from the body.
database_cross_reference: JB:AEO
annotated source: excreta
annotated property: definition

developing epithelium
type: Class
subclass of: developing anatomical structure
subclass of: epithelium
id: AEO:0001007
definition: An epithelium within an embryo or larva that is undergoing a major developmental change.
has_alternative_id: EHDAA2:0004653
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An epithelium within an embryo or larva that is undergoing a major developmental change.
annotated source: developing epithelium
annotated property: definition

neuroepithelium
type: Class
subclass of: developing epithelium
subclass of: Restriction
  on property: has_part
  some values from: columnar/cuboidal epithelial cell
id: AEO:0001008
definition: An embryonic or larval epithelium that is committed to form part of the nervous system.
has_alternative_id: EHDAA2:0004654
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An embryonic or larval epithelium that is committed to form part of the nervous system.
annotated source: neuroepithelium
annotated property: definition

proliferating neuroepithelium
type: Class
subclass of: neuroepithelium
subclass of: Restriction
  on property: has_part
  some values from: columnar/cuboidal epithelial cell
id: AEO:0001009
definition: An epithelium that is undergoing proliferation to provide large numbers of neuronal cells.
has_alternative_id: EHDAA2:0004655
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An epithelium that is undergoing proliferation to provide large numbers of neuronal cells.
annotated source: proliferating neuroepithelium
annotated property: definition

differentiating neuroepithelium
type: Class
subclass of: neuroepithelium
subclass of: Restriction
  on property: has_part
  some values from: neuroglioblast
subclass of: Restriction
  on property: has_part
  some values from: neuroblast
definition: A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells.
id: AEO:0001010
has_alternative_id: EHDAA2:0004656
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells.
database_cross_reference: AEO:JB
annotated source: differentiating neuroepithelium
annotated property: definition

neuronal white matter
type: Class
subclass of: neural tissue
id: AEO:0001011
has_alternative_id: EHDAA2:0004657
definition: Neuronal tissue composed predominantly of axons.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: Neuronal tissue composed predominantly of axons.
annotated source: neuronal white matter
annotated property: definition

neuronal grey matter
type: Class
subclass of: neural tissue
definition: A neuronal tissue composed predominantly of nerve bodies and neuronal support cells.
id: AEO:0001012
has_alternative_id: EHDAA2:0004658
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A neuronal tissue composed predominantly of nerve bodies and neuronal support cells.
database_cross_reference: AEO:JB
annotated source: neuronal grey matter
annotated property: definition

neuronal column
type: Class
subclass of: neuronal grey matter
subclass of: Restriction
  on property: has_part
  some values from: astrocyte
subclass of: Restriction
  on property: has_part
  some values from: microglial cell
subclass of: Restriction
  on property: has_part
  some values from: oligodendrocyte
id: AEO:0001013
definition: An extended columnar domain of predominantly neuronal tissue in the central nervous system.
has_alternative_id: EHDAA2:0004659
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: AEO:JB
annotated target: An extended columnar domain of predominantly neuronal tissue in the central nervous system.
annotated source: neuronal column
annotated property: definition

differentiating neuronal condensation
type: Class
subclass of: developing anatomical structure
subclass of: Restriction
  on property: has_part
  some values from: neuroblast
subclass of: Restriction
  on property: has_part
  some values from: neuroglioblast
definition: A compact group of cells differentiating to become a ganglion or a neuronal nucleus.
id: AEO:0001014
has_alternative_id: EHDAA2:0004660
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A compact group of cells differentiating to become a ganglion or a neuronal nucleus.
database_cross_reference: AEO:JB
annotated source: differentiating neuronal condensation
annotated property: definition

somite
type: Class
subclass of: epithelial vesicle
id: AEO:0001015
definition: An epithelial ball that forms from paraxial mesoderm.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: An epithelial ball that forms from paraxial mesoderm.
database_cross_reference: JB:AEO
annotated source: somite
annotated property: definition

developing mesenchymal structure
type: Class
subclass of: developing anatomical structure
definition: A mesenchyme-derived anatomical entity undergoing a transtion to become another structure.
id: AEO:0001016
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A mesenchyme-derived anatomical entity undergoing a transtion to become another structure.
database_cross_reference: AEO:JB
annotated source: developing mesenchymal structure
annotated property: definition

dermatome
type: Class
subclass of: migrating developing tissue
subclass of: developing mesenchymal structure
definition: A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells.
id: AEO:0001017
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells.
database_cross_reference: AEO:JB
annotated source: dermatome
annotated property: definition

myotome
type: Class
subclass of: migrating developing tissue
subclass of: developing mesenchymal structure
definition: A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells.
id: AEO:0001018
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells.
database_cross_reference: AEO:JB
annotated source: myotome
annotated property: definition

developing germ cell population
type: Class
subclass of: developing anatomical structure
definition: A germ cell population that has not undergone meiosis.
id: AEO:0001019
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A germ cell population that has not undergone meiosis.
database_cross_reference: AEO:JB
annotated source: developing germ cell population
annotated property: definition

reproductive cell population
type: Class
subclass of: simple tissue
subclass of: Restriction
  on property: has_part
  some values from: germ line cell
definition: A population of cells that are predominantly immature or mature germ cells.
id: AEO:0001020
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A population of cells that are predominantly immature or mature germ cells.
database_cross_reference: AEO:JB
annotated source: reproductive cell population
annotated property: definition

stem cell population
type: Class
subclass of: simple tissue
definition: A group of cells capable of regenerating themselves and also of producing one or more populations of differentiated cells.
id: AEO:0001021
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: A group of cells capable of regenerating themselves and also of producing one or more populations of differentiated cells.
database_cross_reference: AEO:JB
annotated source: stem cell population
annotated property: definition

anatomical entity
type: Class
definition: Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
id: CARO:0000000
has_alternative_id: EHDAA2:0003000
has_alternative_id: UBERON:0001062
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
database_cross_reference: CARO:MAH
annotated source: anatomical entity
annotated property: definition

anatomical structure
type: Class
subclass of: material anatomical entity
id: CARO:0000003
has_alternative_id: EHDAA2:0003003
definition: Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome.
has_alternative_id: UBERON:0000061
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome.
annotated source: anatomical structure
annotated property: definition

non-tissue substance
type: Class
subclass of: material anatomical entity
id: CARO:0000004
has_alternative_id: EHDAA2:0003004
definition: Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body.
has_alternative_id: UBERON:0000463
has_obo_namespace: http://www.xspan.org/obo.owl#
has_related_synonym: portion of organism substance

Axiom
database_cross_reference: CARO:MAH
annotated target: Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body.
annotated source: non-tissue substance
annotated property: definition

anatomical space
type: Class
subclass of: immaterial anatomical entity
id: CARO:0000005
has_alternative_id: EHDAA2:0003005
definition: Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures.
has_alternative_id: UBERON:0000464
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures.
annotated source: anatomical space
annotated property: definition

material anatomical entity
type: Class
subclass of: anatomical entity
definition: Anatomical entity that has mass.
id: CARO:0000006
has_alternative_id: EHDAA2:0003006
has_alternative_id: UBERON:0000465
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical entity that has mass.
database_cross_reference: CARO:MAH
annotated source: material anatomical entity
annotated property: definition

immaterial anatomical entity
type: Class
subclass of: anatomical entity
definition: Anatomical entity that has no mass.
id: CARO:0000007
has_alternative_id: EHDAA2:0003007
has_alternative_id: UBERON:0000466
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical entity that has no mass.
database_cross_reference: CARO:MAH
annotated source: immaterial anatomical entity
annotated property: definition

anatomical line
type: Class
subclass of: immaterial anatomical entity
id: CARO:0000008
has_alternative_id: EHDAA2:0003008
definition: Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface.
annotated source: anatomical line
annotated property: definition

anatomical point
type: Class
subclass of: immaterial anatomical entity
id: CARO:0000009
has_alternative_id: EHDAA2:0003009
definition: Non-material anatomical entity of zero dimension, which forms a boundary of an anatomical line or surface.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Non-material anatomical entity of zero dimension, which forms a boundary of an anatomical line or surface.
annotated source: anatomical point
annotated property: definition

anatomical surface
type: Class
subclass of: immaterial anatomical entity
id: CARO:0000010
has_alternative_id: EHDAA2:0003192
definition: Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures.
has_alternative_id: UBERON:0000015
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures.
annotated source: anatomical surface
annotated property: definition

anatomical system
type: Class
subclass of: anatomical group
definition: Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity.
id: CARO:0000011
has_alternative_id: EHDAA2:0003011
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity.
database_cross_reference: CARO:MAH
annotated source: anatomical system
annotated property: definition

multi-cellular organism
type: Class
subclass of: anatomical structure
definition: Anatomical structure that is an individual member of a species and consists of more than one cell.
id: CARO:0000012
has_alternative_id: EHDAA2:0003191
has_alternative_id: UBERON:0000468
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure that is an individual member of a species and consists of more than one cell.
database_cross_reference: JB:DEF
annotated source: multi-cellular organism
annotated property: definition

cell
type: Class
subclass of: anatomical structure
definition: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
id: CARO:0000013
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: CARO:MAH
annotated source: cell
annotated property: definition

cell component
type: Class
subclass of: anatomical structure
subclass of: Restriction
  on property: part_of
  some values from: cell
definition: Anatomical structure that is a direct part of the cell.
id: CARO:0000014
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure that is a direct part of the cell.
database_cross_reference: CARO:MAH
annotated source: cell component
annotated property: definition

compound organ component
type: Class
subclass of: multi-tissue structure
subclass of: Restriction
  on property: part_of
  some values from: compound organ
id: CARO:0000019
has_alternative_id: EHDAA2:0003019
definition: Multi-tissue structure that is part of a compound organ.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Multi-tissue structure that is part of a compound organ.
annotated source: compound organ component
annotated property: definition

simple organ
type: Class
subclass of: multi-tissue structure
id: CARO:0000021
has_alternative_id: EHDAA2:0003190
definition: Multi-tissue structure that is not part of a compound organ.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Multi-tissue structure that is not part of a compound organ.
annotated source: simple organ
annotated property: definition

compound organ
type: Class
subclass of: anatomical structure
definition: Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types.
id: CARO:0000024
has_alternative_id: EHDAA2:0003024
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types.
database_cross_reference: CARO:MAH
annotated source: compound organ
annotated property: definition

male organism
type: Class
subclass of: gonochoristic organism
id: CARO:0000027
definition: Gonochoristic organism that can produce male gametes.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Gonochoristic organism that can produce male gametes.
annotated source: male organism
annotated property: definition

female organism
type: Class
subclass of: gonochoristic organism
id: CARO:0000028
definition: Gonochoristic organism that can produce female gametes.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Gonochoristic organism that can produce female gametes.
annotated source: female organism
annotated property: definition

hermaphroditic organism
type: Class
subclass of: multi-cellular organism
id: CARO:0000029
definition: Multi-cellular organism that can produce both male and female gametes.
has_related_synonym: dioecious organism
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Multi-cellular organism that can produce both male and female gametes.
annotated source: hermaphroditic organism
annotated property: definition

organism subdivision
type: Class
subclass of: anatomical structure
definition: Anatomical structure which is a primary subdivision of whole organism. The mereological sum of these is the whole organism.
id: CARO:0000032
has_alternative_id: EHDAA2:0003032
has_alternative_id: UBERON:0000475
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure which is a primary subdivision of whole organism. The mereological sum of these is the whole organism.
database_cross_reference: CARO:MAH
annotated source: organism subdivision
annotated property: definition

acellular anatomical structure
type: Class
subclass of: anatomical structure
definition: Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue.
id: CARO:0000040
has_alternative_id: EHDAA2:0003040
has_alternative_id: UBERON:0000476
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue.
database_cross_reference: CARO:MAH
annotated source: acellular anatomical structure
annotated property: definition

anatomical cluster
type: Class
subclass of: anatomical group
definition: Anatomical group that has its parts adjacent to one another. Anatomical structure, which has as its parts a heterogeneous collection of organs, organ parts, cells or body part subdivisions that are adjacent to, or continuous with one another; does not constitute an organ, organ system or organ system subdivision, or body part or body part subdivision.
id: CARO:0000041
has_alternative_id: EHDAA2:0003041
has_alternative_id: UBERON:0000477
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical group that has its parts adjacent to one another. Anatomical structure, which has as its parts a heterogeneous collection of organs, organ parts, cells or body part subdivisions that are adjacent to, or continuous with one another; does not constitute an organ, organ system or organ system subdivision, or body part or body part subdivision.
database_cross_reference: CARO:MAH
annotated source: anatomical cluster
annotated property: definition

extraembryonic structure
type: Class
subclass of: anatomical structure
definition: Anatomical structure that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo.
id: CARO:0000042
has_alternative_id: EHDAA2:0003042
has_alternative_id: UBERON:0000478
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo.
database_cross_reference: CARO:MAH
annotated source: extraembryonic structure
annotated property: definition

simple tissue
type: Class
subclass of: anatomical structure
definition: Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.
id: CARO:0000043
has_alternative_id: EHDAA2:0003043
has_alternative_id: UBERON:0000479
has_obo_namespace: http://www.xspan.org/obo.owl#
has_related_synonym: portion of tissue.

Axiom
annotated target: Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships.
database_cross_reference: CARO:MAH
annotated source: simple tissue
annotated property: definition

sequential hermaphroditic organism
type: Class
subclass of: hermaphroditic organism
id: CARO:0000045
definition: Hermaphroditic organism that produces gametes first of one sex, and then later of the other sex.
has_related_synonym: consecutive hermaphroditic organism
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Hermaphroditic organism that produces gametes first of one sex, and then later of the other sex.
annotated source: sequential hermaphroditic organism
annotated property: definition

synchronous hermaphroditic organism
type: Class
subclass of: hermaphroditic organism
id: CARO:0000046
definition: Hermaphroditic organism that produces both male and female gametes at the same time.
has_obo_namespace: http://www.xspan.org/obo.owl#
has_related_synonym: serially hermaphroditic organism

Axiom
database_cross_reference: CARO:MAH
annotated target: Hermaphroditic organism that produces both male and female gametes at the same time.
annotated source: synchronous hermaphroditic organism
annotated property: definition

gonochoristic organism
type: Class
subclass of: multi-cellular organism
id: CARO:0000048
definition: Multi-cellular organism that has male and female sexes.
has_obo_namespace: http://www.xspan.org/obo.owl#
has_related_synonym: monoecious organism

Axiom
database_cross_reference: CARO:MAH
annotated target: Multi-cellular organism that has male and female sexes.
annotated source: gonochoristic organism
annotated property: definition

protandrous hermaphroditic organism
type: Class
subclass of: sequential hermaphroditic organism
id: CARO:0000049
definition: Sequential hermaphroditic organism that produces gametes first of the male sex, and then later of the female sex.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Sequential hermaphroditic organism that produces gametes first of the male sex, and then later of the female sex.
annotated source: protandrous hermaphroditic organism
annotated property: definition

protogynous hermaphroditic organism
type: Class
subclass of: sequential hermaphroditic organism
id: CARO:0000050
definition: Sequential hermaphroditic organism that produces gametes first of the female sex, and then later of the male sex.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Sequential hermaphroditic organism that produces gametes first of the female sex, and then later of the male sex.
annotated source: protogynous hermaphroditic organism
annotated property: definition

anatomical group
type: Class
subclass of: anatomical structure
definition: Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue.
id: CARO:0000054
has_alternative_id: EHDAA2:0003054
has_alternative_id: UBERON:0000480
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue.
database_cross_reference: CARO:MAH
annotated source: anatomical group
annotated property: definition

multi-tissue structure
type: Class
subclass of: anatomical structure
definition: Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types.
id: CARO:0000055
has_alternative_id: EHDAA2:0003055
has_alternative_id: UBERON:0000481
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types.
database_cross_reference: CARO:MAH
annotated source: multi-tissue structure
annotated property: definition

cell space
type: Class
subclass of: anatomical space
definition: Anatomical space that is part of a cell.
id: CARO:0000062
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Anatomical space that is part of a cell.
database_cross_reference: CARO:mah
annotated source: cell space
annotated property: definition

asexual organism
type: Class
subclass of: multi-cellular organism
id: CARO:0000063
definition: Multi-cellular organism that does not produce gametes.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Multi-cellular organism that does not produce gametes.
annotated source: asexual organism
annotated property: definition

single cell organism
type: Class
subclass of: cell
id: CARO:0000064
definition: Cell that is an individual member of a species.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Cell that is an individual member of a species.
annotated source: single cell organism
annotated property: definition

basal lamina
type: Class
subclass of: acellular anatomical structure
subclass of: Restriction
  on property: part_of
  some values from: epithelium
definition: Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue.
id: CARO:0000065
has_alternative_id: EHDAA2:0003065
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
annotated target: Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue.
database_cross_reference: CARO:MAH
annotated source: basal lamina
annotated property: definition

epithelium
type: Class
subclass of: simple tissue
id: CARO:0000066
has_alternative_id: EHDAA2:0003066
definition: Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina.
annotated source: epithelium
annotated property: definition

simple cuboidal epithelium
type: Class
subclass of: unilaminar epithelium
subclass of: Restriction
  on property: has_part
  some values from: columnar/cuboidal epithelial cell
id: CARO:0000067
has_alternative_id: EHDAA2:0003067
definition: Unilaminar epithelium that consists of a single layer of cuboidal cells.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Unilaminar epithelium that consists of a single layer of cuboidal cells.
annotated source: simple cuboidal epithelium
annotated property: definition

columnar epithelium
type: Class
subclass of: unilaminar epithelium
id: CARO:0000068
has_alternative_id: EHDAA2:0003068
definition: Unilaminar epithelium that consists of a single layer of columnar cells.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Unilaminar epithelium that consists of a single layer of columnar cells.
annotated source: columnar epithelium
annotated property: definition

multilaminar epithelium
type: Class
subclass of: epithelium
id: CARO:0000069
has_alternative_id: EHDAA2:0003069
definition: Epithelium that consists of more than one layer of epithelial cells.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Epithelium that consists of more than one layer of epithelial cells.
annotated source: multilaminar epithelium
annotated property: definition

simple squamous epithelium
type: Class
subclass of: unilaminar epithelium
subclass of: Restriction
  on property: has_part
  some values from: squamous epithelial cell
id: CARO:0000070
has_alternative_id: EHDAA2:0003070
definition: Unilaminar epithelium that consists of a single layer of squamous cells.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Unilaminar epithelium that consists of a single layer of squamous cells.
annotated source: simple squamous epithelium
annotated property: definition

atypical epithelium
type: Class
subclass of: epithelium
subclass of: Restriction
  on property: has_part
  some values from: epithelial cell
id: CARO:0000071
has_alternative_id: EHDAA2:0003071
definition: Epithelium that consists of epithelial cells not arranged in one ore more layers.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Epithelium that consists of epithelial cells not arranged in one ore more layers.
annotated source: atypical epithelium
annotated property: definition

cavitated compound organ
type: Class
subclass of: compound organ
id: CARO:0000072
definition: Compound organ that contains one or more macroscopic anatomical spaces.
has_alternative_id: EHDAA2:0003072
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Compound organ that contains one or more macroscopic anatomical spaces.
annotated source: cavitated compound organ
annotated property: definition

unilaminar epithelium
type: Class
subclass of: epithelium
id: CARO:0000073
has_alternative_id: EHDAA2:0003073
definition: Epithelium that consists of a single layer of epithelial cells.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Epithelium that consists of a single layer of epithelial cells.
annotated source: unilaminar epithelium
annotated property: definition

solid compound organ
type: Class
subclass of: compound organ
id: CARO:0000074
definition: Compound organ that does not contain macroscopic anatomical spaces.
has_alternative_id: EHDAA2:0003074
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
annotated target: Compound organ that does not contain macroscopic anatomical spaces.
annotated source: solid compound organ
annotated property: definition

epithelial cell
type: Class
subclass of: cell
id: CARO:0000077
definition: Cell which has as its part a cytoskeleton that allows for tight cell to cell contact and which has apical-basal cell polarity.
has_obo_namespace: http://www.xspan.org/obo.owl#

Axiom
database_cross_reference: CARO:MAH
database_cross_reference: CL:0000066
annotated target: Cell which has as its part a cytoskeleton that allows for tight cell to cell contact and which has apical-basal cell polarity.
annotated source: epithelial cell
annotated property: definition

cell
type: Class
definition: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
id: CL:0000000
has_obo_namespace: cell

Axiom
annotated target: Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
database_cross_reference: CARO:mah
annotated source: cell
annotated property: definition

cell in vivo
type: Class
subclass of: cell
id: CL:0000003
has_obo_namespace: cell

cell by class
type: Class
subclass of: cell in vivo
id: CL:0000012
has_obo_namespace: cell

male germ cell
type: Class
subclass of: germ cell
definition: A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte.
id: CL:0000015
has_obo_namespace: cell
has_related_synonym: nurse cell

Axiom
annotated target: A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:15848391
annotated source: male germ cell
annotated property: definition

female germ cell
type: Class
subclass of: germ cell
id: CL:0000021
definition: Female germ cell is a germ cell that supports female gamete production.
has_obo_namespace: cell

Axiom
annotated target: Female germ cell is a germ cell that supports female gamete production.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:11023867
database_cross_reference: PMID:20454446
annotated source: female germ cell
annotated property: definition

neuron neural crest derived
type: Class
subclass of: neuron
id: CL:0000029
has_obo_namespace: cell

neuroblast
type: Class
subclass of: non-terminally differentiated cell
id: CL:0000031
has_obo_namespace: cell

stem cell
type: Class
subclass of: cell by function
definition: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
id: CL:0000034
has_obo_namespace: cell

Axiom
annotated target: A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:A.11.872
annotated source: stem cell
annotated property: definition

germ line cell
type: Class
subclass of: cell by function
definition: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.
id: CL:0000039
comment: Originally this term had some plant germ line cell children
has_obo_namespace: cell

Axiom
annotated target: A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544
annotated source: germ line cell
annotated property: definition

non-terminally differentiated cell
type: Class
subclass of: cell by class
definition: A precursor cell with a limited number of potential fates.
id: CL:0000055
has_related_synonym: blast cell
has_obo_namespace: cell

Axiom
annotated target: A precursor cell with a limited number of potential fates.
database_cross_reference: SANBI:mhl
annotated source: non-terminally differentiated cell
annotated property: definition

fibroblast
type: Class
subclass of: connective tissue cell
definition: A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
id: CL:0000057
has_obo_namespace: cell

Axiom
annotated target: A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
database_cross_reference: ISBN:0517223651
database_cross_reference: MESH:A.11.329.228
database_cross_reference: http://63.198.234.228/OpenFMA/Fibroblast.html
annotated source: fibroblast
annotated property: definition

chondroblast
type: Class
subclass of: non-terminally differentiated cell
subclass of: collagen secreting cell
definition: An immature cartilage-producing cell found in growing cartilage.
id: CL:0000058
has_obo_namespace: cell
has_related_synonym: chrondoplast

Axiom
annotated target: An immature cartilage-producing cell found in growing cartilage.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256
annotated source: chondroblast
annotated property: definition

osteoblast
type: Class
subclass of: non-terminally differentiated cell
subclass of: connective tissue cell
definition: A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
id: CL:0000062
has_obo_namespace: cell

Axiom
annotated target: A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
database_cross_reference: MESH:A.11.329.629
annotated source: osteoblast
annotated property: definition

cell by histology
type: Class
subclass of: cell by class
definition: A classification of cells by their microscopic appearance.
id: CL:0000063
has_obo_namespace: cell

Axiom
annotated target: A classification of cells by their microscopic appearance.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm
annotated source: cell by histology
annotated property: definition

epithelial cell
type: Class
subclass of: cell by histology
definition: A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.
id: CL:0000066
has_related_synonym: Epitheliocyte
has_obo_namespace: cell

Axiom
annotated target: A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm
database_cross_reference: MESH:A.11.436
annotated source: epithelial cell
annotated property: definition

duct epithelial cell
type: Class
subclass of: epithelial cell
subclass of: somatic cell
id: CL:0000068
has_obo_namespace: cell

blood vessel endothelial cell
type: Class
subclass of: squamous epithelial cell
definition: An endothelial cell that lines the vasculature.
id: CL:0000071
has_related_synonym: Cuboidal endothelial cell of vascular tree
has_obo_namespace: cell

Axiom
annotated target: An endothelial cell that lines the vasculature.
database_cross_reference: GOC:tfm
annotated source: blood vessel endothelial cell
annotated property: definition

columnar/cuboidal epithelial cell
type: Class
subclass of: epithelial cell
subclass of: somatic cell
id: CL:0000075
has_obo_namespace: cell

squamous epithelial cell
type: Class
subclass of: epithelial cell
id: CL:0000076
has_obo_namespace: cell

stratified epithelial cell
type: Class
subclass of: epithelial cell
subclass of: somatic cell
id: CL:0000079
has_obo_namespace: cell

circulating cell
type: Class
subclass of: cell by function
definition: A cell which moves among different tissues of the body, via blood, lymph, or other medium.
id: CL:0000080
has_obo_namespace: cell

Axiom
annotated target: A cell which moves among different tissues of the body, via blood, lymph, or other medium.
database_cross_reference: GOC:add
annotated source: circulating cell
annotated property: definition

blood cell
type: Class
subclass of: hematopoietic cell
definition: A cell found predominately in the blood.
id: CL:0000081
has_obo_namespace: cell

Axiom
annotated target: A cell found predominately in the blood.
database_cross_reference: GOC:add
database_cross_reference: GOC:tfm
annotated source: blood cell
annotated property: definition

neuron associated cell
type: Class
subclass of: neural cell
id: CL:0000095
has_obo_namespace: cell

interneuron
type: Class
subclass of: neuron
id: CL:0000099
definition: Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
has_obo_namespace: cell

Axiom
database_cross_reference: GOC:tfm
database_cross_reference: MESH:A.08.663.358
annotated target: Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.
annotated source: interneuron
annotated property: definition

sensory neuron
type: Class
subclass of: afferent neuron
definition: Any neuron having a sensory function; an afferent neuron conveying sensory impulses.
id: CL:0000101
has_obo_namespace: cell

Axiom
annotated target: Any neuron having a sensory function; an afferent neuron conveying sensory impulses.
database_cross_reference: ISBN:0721662544
annotated source: sensory neuron
annotated property: definition

autonomic neuron
type: Class
subclass of: neuron
definition: A neruon whose cell body is within an autonomic ganglion.
id: CL:0000107
has_obo_namespace: cell

Axiom
annotated target: A neruon whose cell body is within an autonomic ganglion.
database_cross_reference: GOC:tfm
annotated source: autonomic neuron
annotated property: definition

glial cell
type: Class
subclass of: neuron associated cell
definition: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.
id: CL:0000125
has_obo_namespace: cell
has_related_synonym: neuroglia
has_related_synonym: neuroglial cell

Axiom
annotated target: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons.
database_cross_reference: MESH:A.08.637
annotated source: glial cell
annotated property: definition

macroglial cell
type: Class
subclass of: glial cell (sensu Vertebrata)
definition: A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together.
id: CL:0000126
has_related_synonym: Macrogliocyte
has_obo_namespace: cell

Axiom
annotated target: A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544
annotated source: macroglial cell
annotated property: definition

astrocyte
type: Class
subclass of: oligodendrocyte
definition: A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury.
id: CL:0000127
has_related_synonym: astrocytic glia
has_obo_namespace: cell

Axiom
annotated target: A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury.
database_cross_reference: GOC:_tfm
database_cross_reference: GOC:dsd
database_cross_reference: MESH:A.08.637.200
database_cross_reference: MESH:D001253
database_cross_reference: PMID:11746784
database_cross_reference: PMID:12162730
database_cross_reference: PMID:12898703
database_cross_reference: PMID:20942978
annotated source: astrocyte
annotated property: definition

oligodendrocyte
type: Class
subclass of: macroglial cell
definition: A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.
id: CL:0000128
has_obo_namespace: cell
has_related_synonym: oligodendroglia

Axiom
annotated target: A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.
database_cross_reference: MESH:A.08.637.600
annotated source: oligodendrocyte
annotated property: definition

microglial cell
type: Class
subclass of: glial cell (sensu Vertebrata)
definition: A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive.
id: CL:0000129
has_related_synonym: MF.microglia.CNS
has_related_synonym: brain macrophage
has_related_synonym: brain-resident macrophage
has_obo_namespace: cell
has_related_synonym: hortega cells
has_related_synonym: microglia
has_related_synonym: microgliocyte

Axiom
database_cross_reference: http://www.copewithcytokines.de/
annotated target: microgliocyte
annotated source: microglial cell
annotated property: has_related_synonym

Axiom
annotated target: hortega cells
database_cross_reference: http://www.copewithcytokines.de/
annotated source: microglial cell
annotated property: has_related_synonym

Axiom
annotated target: A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive.
database_cross_reference: GOC:add
database_cross_reference: GOC:dsd
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721601464
database_cross_reference: MESH:D017628
database_cross_reference: PMID:11517395
database_cross_reference: PMID:12430718
database_cross_reference: PMID:14561199
database_cross_reference: PMID:14612429
database_cross_reference: PMID:16177057
database_cross_reference: PMID:19461673
database_cross_reference: PMID:2089275
annotated source: microglial cell
annotated property: definition

mesenchymal cell
type: Class
subclass of: cell by histology
definition: A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
has_related_synonym: BMSC
has_related_synonym: CFU-F
id: CL:0000134
has_alternative_id: CL:0002452
has_related_synonym: MSC
has_related_synonym: Stem Cells, Mesenchymal
has_related_synonym: bone marrow stromal cells
has_obo_namespace: cell
has_related_synonym: colony-forming unit-fibroblast
has_related_synonym: marrow stromal cells
has_related_synonym: mesenchymal precursor cell
has_related_synonym: mesenchymal progenitor cells
has_related_synonym: mesenchymal stem cell
has_related_synonym: mesenchymal stromal cell
has_related_synonym: mesenchymal stromal cells

Axiom
database_cross_reference: MESH:D044982
annotated target: mesenchymal progenitor cells
annotated source: mesenchymal cell
annotated property: has_related_synonym

Axiom
annotated target: MSC
database_cross_reference: PMID:11378515
annotated source: mesenchymal cell
annotated property: has_related_synonym

Axiom
database_cross_reference: PMID:11378515
annotated target: marrow stromal cells
annotated source: mesenchymal cell
annotated property: has_related_synonym

Axiom
database_cross_reference: MESH:D044982
annotated target: Stem Cells, Mesenchymal
annotated source: mesenchymal cell
annotated property: has_related_synonym

Axiom
annotated target: A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs.
database_cross_reference: FB:ma
database_cross_reference: GOC:dsd
database_cross_reference: PMCID:PMC2613570
database_cross_reference: PMID:10102814j
database_cross_reference: PMID:16923606
database_cross_reference: PMID:_17986482
database_cross_reference: PMID:_19960544
database_cross_reference: http://en.wikipedia.org/wiki/Mesenchymal_stem_cell
database_cross_reference: http://www.copewithcytokines.de/cope.cgi
annotated source: mesenchymal cell
annotated property: definition

fat cell
type: Class
subclass of: connective tissue cell
definition: A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.
id: CL:0000136
has_alternative_id: CL:0000450
has_related_synonym: adipocyte
has_related_synonym: adipose cell
has_obo_namespace: cell

Axiom
annotated target: A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides.
database_cross_reference: MESH:A.11.329.114
annotated source: fat cell
annotated property: definition

chondrocyte
type: Class
subclass of: collagen secreting cell
id: CL:0000138
definition: Polymorphic cell that form cartilage.
has_related_synonym: cartilage cell
has_obo_namespace: cell

Axiom
database_cross_reference: MESH:A.11.329.171
annotated target: Polymorphic cell that form cartilage.
annotated source: chondrocyte
annotated property: definition

cell by function
type: Class
subclass of: cell by class
definition: A classification of cells by their primary end goal or behavior.
id: CL:0000144
has_obo_namespace: cell

Axiom
annotated target: A classification of cells by their primary end goal or behavior.
database_cross_reference: FB:ma
annotated source: cell by function
annotated property: definition

secretory cell
type: Class
subclass of: cell by function
definition: A cell that specializes in controlled release of one or more substances.
id: CL:0000151
has_obo_namespace: cell

Axiom
annotated target: A cell that specializes in controlled release of one or more substances.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544
annotated source: secretory cell
annotated property: definition

neuroendocrine cell
type: Class
subclass of: electrically responsive cell
definition: An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals.
id: CL:0000165
has_obo_namespace: cell
has_related_synonym: neurosecretory cell

Axiom
annotated target: An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals.
database_cross_reference: MESH:A.06.688
annotated source: neuroendocrine cell
annotated property: definition

muscle cell
type: Class
subclass of: electrically responsive cell
subclass of: somatic cell
definition: A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
id: CL:0000187
has_obo_namespace: cell
has_related_synonym: myocyte

Axiom
annotated target: A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
database_cross_reference: MESH:A.11.620
annotated source: muscle cell
annotated property: definition

skeletal muscle cell
type: Class
subclass of: muscle cell
definition: A somatic cell located in skeletal muscle.
id: CL:0000188
has_obo_namespace: cell

Axiom
annotated target: A somatic cell located in skeletal muscle.
database_cross_reference: GOC:tfm
annotated source: skeletal muscle cell
annotated property: definition

smooth muscle cell
type: Class
subclass of: muscle cell
definition: A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).
has_alternative_id: CL:0000191
id: CL:0000192
has_related_synonym: SMCs
has_obo_namespace: cell
has_related_synonym: myocytes, smooth muscle
has_related_synonym: non-striated muscle cell
has_related_synonym: smooth muscle fiber

Axiom
database_cross_reference: MESH:D032389
annotated target: myocytes, smooth muscle
annotated source: smooth muscle cell
annotated property: has_related_synonym

Axiom
database_cross_reference: PMID:9315361
annotated target: SMCs
annotated source: smooth muscle cell
annotated property: has_related_synonym

Axiom
annotated target: A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast).
database_cross_reference: MESH:A.11.620.520
database_cross_reference: MESH:D032389
database_cross_reference: PMID:9315361
annotated source: smooth muscle cell
annotated property: definition

flight muscle cell
type: Class
subclass of: muscle cell
id: CL:0000196
has_obo_namespace: cell

electrically active cell
type: Class
subclass of: cell by function
definition: A cell whose function is determined by the generation or the reception of an electric signal.
id: CL:0000211
has_obo_namespace: cell

Axiom
annotated target: A cell whose function is determined by the generation or the reception of an electric signal.
database_cross_reference: FB:ma
annotated source: electrically active cell
annotated property: definition

cell by nuclear number
type: Class
subclass of: cell by class
definition: A classification of cells by the number of their nuclei.
id: CL:0000224
has_obo_namespace: cell

Axiom
annotated target: A classification of cells by the number of their nuclei.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm
annotated source: cell by nuclear number
annotated property: definition

multinucleate cell
type: Class
subclass of: nucleate cell
definition: A cell with more than one nucleus.
id: CL:0000228
has_obo_namespace: cell
has_related_synonym: syncitium
has_related_synonym: syncytial cell
has_related_synonym: syncytium

Axiom
annotated target: A cell with more than one nucleus.
database_cross_reference: FB:ma
annotated source: multinucleate cell
annotated property: definition

glial cell (sensu Vertebrata)
type: Class
subclass of: glial cell
definition: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.
id: CL:0000243
has_obo_namespace: cell

Axiom
annotated target: A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear.
database_cross_reference: MESH:A.08.637
annotated source: glial cell (sensu Vertebrata)
annotated property: definition

extracellular matrix secreting cell
type: Class
subclass of: secretory cell
subclass of: stromal cell
id: CL:0000327
has_obo_namespace: cell

mesenchyme condensation cell
type: Class
subclass of: mesenchymal cell
definition: A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.
id: CL:0000335
has_obo_namespace: cell

Axiom
annotated target: A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:5025404
annotated source: mesenchyme condensation cell
annotated property: definition

electrically responsive cell
type: Class
subclass of: electrically active cell
definition: A cell whose function is determined by its response to an electric signal.
id: CL:0000393
has_obo_namespace: cell

Axiom
annotated target: A cell whose function is determined by its response to an electric signal.
database_cross_reference: FB:ma
annotated source: electrically responsive cell
annotated property: definition

cell by ploidy
type: Class
subclass of: cell by class
definition: A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei.
id: CL:0000414
has_obo_namespace: cell

Axiom
annotated target: A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei.
database_cross_reference: FB:ma
database_cross_reference: GOC:tfm
annotated source: cell by ploidy
annotated property: definition

obliquely striated muscle cell
type: Class
subclass of: striated muscle cell
id: CL:0000444
has_obo_namespace: cell

apoptosis fated cell
type: Class
subclass of: cell by function
id: CL:0000445
has_obo_namespace: cell

neuroglioblast
type: Class
subclass of: non-terminally differentiated cell
id: CL:0000468
has_obo_namespace: cell

stromal cell
type: Class
subclass of: connective tissue cell
definition: A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.
id: CL:0000499
has_obo_namespace: cell

Axiom
annotated target: A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:A.11.329.830
annotated source: stromal cell
annotated property: definition

syncytiotrophoblast cell
type: Class
subclass of: multinucleate cell
definition: A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.
id: CL:0000525
has_obo_namespace: cell
has_related_synonym: plasmidotrophoblast
has_related_synonym: syncytial trophoblast
has_related_synonym: syntrophoblast

Axiom
annotated target: A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0323052908
annotated source: syncytiotrophoblast cell
annotated property: definition

afferent neuron
type: Class
subclass of: neuron
definition: A neuron which conveys sensory information centrally from the periphery.
id: CL:0000526
has_obo_namespace: cell
has_related_synonym: input neuron

Axiom
annotated target: A neuron which conveys sensory information centrally from the periphery.
database_cross_reference: GOC:tfm
database_cross_reference: MESH:A.08.663.650
annotated source: afferent neuron
annotated property: definition

efferent neuron
type: Class
subclass of: neuron
definition: A neuron which sends impulses peripherally to activate muscles or secretory cells.
id: CL:0000527
has_obo_namespace: cell
has_related_synonym: output neuron

Axiom
annotated target: A neuron which sends impulses peripherally to activate muscles or secretory cells.
database_cross_reference: MESH:A.08.663.655
annotated source: efferent neuron
annotated property: definition

neuron
type: Class
subclass of: electrically responsive cell
id: CL:0000540
definition: The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
has_obo_namespace: cell
has_related_synonym: nerve cell

Axiom
database_cross_reference: MESH:A.08.663
database_cross_reference: MESH:D009474
annotated target: The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
annotated source: neuron
annotated property: definition

germ cell
type: Class
subclass of: germ line cell
id: CL:0000586
definition: The reproductive cell in multicellular organisms.
has_obo_namespace: cell

Axiom
database_cross_reference: MESH:A.05.360.490
annotated target: The reproductive cell in multicellular organisms.
annotated source: germ cell
annotated property: definition

cuticle secreting cell
type: Class
subclass of: epithelial cell
subclass of: extracellular matrix secreting cell
definition: An epithelial cell that secretes cuticle.
id: CL:0000658
has_obo_namespace: cell

Axiom
annotated target: An epithelial cell that secretes cuticle.
database_cross_reference: GOC:tfm
annotated source: cuticle secreting cell
annotated property: definition

collagen secreting cell
type: Class
subclass of: extracellular matrix secreting cell
definition: An extracellular matrix secreting cell that secretes collagen.
id: CL:0000667
has_obo_namespace: cell

Axiom
annotated target: An extracellular matrix secreting cell that secretes collagen.
database_cross_reference: GOC:tfm
annotated source: collagen secreting cell
annotated property: definition

primordial germ cell
type: Class
subclass of: germ line cell
definition: A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.
id: CL:0000670
has_related_synonym: Gonocyte
has_related_synonym: Primitive germ cell
has_obo_namespace: cell

Axiom
annotated target: A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.
database_cross_reference: GOC:tfm
database_cross_reference: PMID:1381289
annotated source: primordial germ cell
annotated property: definition

muscle precursor cell
type: Class
subclass of: non-terminally differentiated cell
subclass of: somatic cell
id: CL:0000680
has_obo_namespace: cell

striated muscle cell
type: Class
subclass of: muscle cell
id: CL:0000737
definition: Muscle cell which has as its direct parts myofilaments organized into sarcomeres.
has_obo_namespace: cell

Axiom
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544
annotated target: Muscle cell which has as its direct parts myofilaments organized into sarcomeres.
annotated source: striated muscle cell
annotated property: definition

cardiac muscle cell
type: Class
subclass of: striated muscle cell
definition: A myocyte located in the heart. The contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.
id: CL:0000746
has_related_synonym: cardiac myocyte
has_related_synonym: cardiocyte
has_related_synonym: cardiomyocyte
has_obo_namespace: cell
has_related_synonym: heart muscle cell

Axiom
annotated target: A myocyte located in the heart. The contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0323052908
annotated source: cardiac muscle cell
annotated property: definition

hematopoietic cell
type: Class
subclass of: somatic cell
definition: A cell of a hematopoietic lineage.
id: CL:0000988
has_obo_namespace: cell
has_related_synonym: haematopoietic cell
has_related_synonym: haemopoietic cell
has_related_synonym: hemopoietic cell

Axiom
annotated target: A cell of a hematopoietic lineage.
database_cross_reference: GOC:add
database_cross_reference: GO_REF:0000031
annotated source: hematopoietic cell
annotated property: definition

nucleate cell
type: Class
subclass of: cell by nuclear number
definition: A cell containing at least one nucleus.
id: CL:0002242
has_obo_namespace: cell

Axiom
annotated target: A cell containing at least one nucleus.
database_cross_reference: GOC:tfm
annotated source: nucleate cell
annotated property: definition

neural cell
type: Class
subclass of: somatic cell
definition: A cell that is part of the nervous system.
id: CL:0002319
has_obo_namespace: cell

Axiom
annotated target: A cell that is part of the nervous system.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256
annotated source: neural cell
annotated property: definition

connective tissue cell
type: Class
subclass of: somatic cell
definition: A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.
id: CL:0002320
has_alternative_id: CL:1000406
has_obo_namespace: cell

Axiom
annotated target: A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0618947256
annotated source: connective tissue cell
annotated property: definition

somatic cell
type: Class
subclass of: cell by function
definition: A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).
id: CL:0002371
has_obo_namespace: cell

Axiom
annotated target: A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0721662544
annotated source: somatic cell
annotated property: definition

myotube
type: Class
subclass of: skeletal muscle cell
subclass of: multinucleate cell
subclass of: striated muscle cell
definition: A myotube is a multinucleated cells that is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
has_alternative_id: CL:0000369
id: CL:0002372
has_obo_namespace: cell
has_related_synonym: myotubule
has_related_synonym: single cell sarcomere
has_related_synonym: skeletal muscle fiber

Axiom
annotated target: A myotube is a multinucleated cells that is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
database_cross_reference: GOC:tfm
database_cross_reference: ISBN:0323052908
annotated source: myotube
annotated property: definition

Schwann cell
type: Class
subclass of: glial cell (sensu Vertebrata)
definition: A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function.
id: CL:0002573
has_obo_namespace: cell

Axiom
annotated target: A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function.
database_cross_reference: GOC:tfm
annotated source: Schwann cell
annotated property: definition