04:07:2013 20:24 1.2 OBO-Edit 2.1.1-beta7 anatomical_entity_ontology anatomical_entity_ontology jonathanbard this version corrects the namespace and includes some flybase alt_IDs definition has_alternative_id database_cross_reference has_obo_format_version has_obo_namespace has_related_synonym derives_from anatomical_entity_ontology derives_from descends anatomical_entity_ontology descends develops_from anatomical_entity_ontology develops_from endStage anatomical_entity_ontology endStage hasMapping anatomical_entity_ontology hasMapping has_part anatomical_entity_ontology has_part isReferenceForMapping anatomical_entity_ontology isReferenceForMapping part_of anatomical_entity_ontology part_of startStage anatomical_entity_ontology startStage subEventOf anatomical_entity_ontology subEventOf type anatomical_entity_ontology type single-cell tissue AEO:0000013 Anatomical structure composed of a single cell. EHDAA2:0003013 http://www.xspan.org/obo.owl# Anatomical structure composed of a single cell. CARO:MAH lumen of tube AEO:0000078 EHDAA2:0003078 The inner space within a tube. UBERON:0005082 http://www.xspan.org/obo.owl# tube lumen AEO:JB The inner space within a tube. lumen of epithelial sac A small cavity bounded by an epithelium. AEO:0000079 EHDAA2:0003079 cavity of vesicle http://www.xspan.org/obo.owl# A small cavity bounded by an epithelium. AEO:JB foramen A hole in a tissue. AEO:0000080 EHDAA2:0003080 http://www.xspan.org/obo.owl# A hole in a tissue. AEO:JB matrix-based tissue A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified. AEO:0000081 EHDAA2:0003081 http://www.xspan.org/obo.owl# A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified. AEO:JB bone AEO:0000082 EHDAA2:0003082 Ossified structure that is predominantly extracellular matrix and forms part of the support system of the body. http://www.xspan.org/obo.owl# AEO:JB Ossified structure that is predominantly extracellular matrix and forms part of the support system of the body. endochondral bone AEO:0000083 Bone that is preformed in cartilage. EHDAA2:0003083 http://www.xspan.org/obo.owl# AEO:JB Bone that is preformed in cartilage. VAO:0000145 membrane bone AEO:0000085 Bone that forms directly from mesenchyme. EHDAA2:0003085 http://www.xspan.org/obo.owl# AEO:JB Bone that forms directly from mesenchyme. VAO:0000023 sesamoid bone AEO:0000086 An endochondral bone that forms within tendenous or ligamentous matrix. EHDAA2:0003086 http://www.xspan.org/obo.owl# AEO:JB An endochondral bone that forms within tendenous or ligamentous matrix. VAO:0000137 cartilage AEO:0000087 Dense connective tissue made primarily of type II collagen. EHDAA2:0003087 http://www.xspan.org/obo.owl# AEO:JB Dense connective tissue made primarily of type II collagen. VAO:0000040 ligament A strap of predominantly extracellular matrix connecting two bones. AEO:0000090 EHDAA2:0003090 http://www.xspan.org/obo.owl# A strap of predominantly extracellular matrix connecting two bones. AEO:JB tendon A strap of predominantly extracellular matrix connecting a muscle to a bone. AEO:0000091 EHDAA2:0003091 http://www.xspan.org/obo.owl# A strap of predominantly extracellular matrix connecting a muscle to a bone. AEO:JB aponeurosis A sheet of extracellular matrix. AEO:0000092 EHDAA2:0003092 http://www.xspan.org/obo.owl# A sheet of extracellular matrix. AEO:JB non-connected functional system AEO:0000093 An anatomical group whose component structures share a common function. EHDAA2:0003093 FBbt:00007278 http://www.xspan.org/obo.owl# AEO:JB An anatomical group whose component structures share a common function. sense organ AEO:0000094 EHDAA2:0003094f FBbt:00005155 Multicellular anatomical structure with largely bona fide boundary that transduces some sensory stimulus to the nervous system. http://www.xspan.org/obo.owl# AEO:JB Multicellular anatomical structure with largely bona fide boundary that transduces some sensory stimulus to the nervous system. fluid-based anatomical entity AEO:0000095 EHDAA2:0003095 Fluid anatomical entity containing cells. http://www.xspan.org/obo.owl# AEO:JB Fluid anatomical entity containing cells. gland A multi-tissue structure that produces a secretion for use elsewhere in the body. AEO:0000096 EHDAA2:0003096 http://www.xspan.org/obo.owl# A multi-tissue structure that produces a secretion for use elsewhere in the body. AEO:JB ducted gland A gland that releases its secretion through a duct. AEO:0000097 EHDAA2:0003097 exocrine gland. http://www.xspan.org/obo.owl# A gland that releases its secretion through a duct. AEO:JB ductless gland A gland that releases its secretion directly into the bloodstream, or equivalent for an invertebrate. AEO:0000098 EHDAA2:0003098 endocrine gland. http://www.xspan.org/obo.owl# A gland that releases its secretion directly into the bloodstream, or equivalent for an invertebrate. AEO:JB AEO:JB endocrine gland. keratin-based structure AEO:0000099 Acellular anatomical structure whose predominant constituent is keratin. EHDAA2:0003099 http://www.xspan.org/obo.owl# AEO:JB Acellular anatomical structure whose predominant constituent is keratin. chitin-based structure AEO:0000100 Acellular anatomical structure whose predominant constituent is chitin. EHDAA2:0003100 http://www.xspan.org/obo.owl# AEO:JB Acellular anatomical structure whose predominant constituent is chitin. body AEO:0000103 EHDAA2:0003103 The region of the organism associated with the visceral organs. http://www.xspan.org/obo.owl# AEO:JB The region of the organism associated with the visceral organs. head AEO:0000106 EHDAA2:0003106 The region of the body containing the brain and mouth. http://www.xspan.org/obo.owl# AEO:JB The region of the body containing the brain and mouth. neck AEO:0000108 EHDAA2:0003108 The region of the body connecting the head and the body. http://www.xspan.org/obo.owl# AEO:JB The region of the body connecting the head and the body. tail AEO:0000109 An external caudal extension of the body. EHDAA2:0003109 http://www.xspan.org/obo.owl# AEO:JB An external caudal extension of the body. mesothelium AEO:0000111 EHDAA2:0003111 Epithelium derived from mesenchyme. http://www.xspan.org/obo.owl# AEO:JB Epithelium derived from mesenchyme. epithelial tube AEO:0000114 An epithelial structure capable of allowing fluid flow. EHDAA2:0003114 http://www.xspan.org/obo.owl# AEO:JB An epithelial structure capable of allowing fluid flow. epithelial sac AEO:0000115 An epithelial pouch with a single opening. EHDAA2:0003115 http://www.xspan.org/obo.owl# AEO:JB An epithelial pouch with a single opening. arborising epithelial duct system A group of connected epithelial tubes with a single portal. AEO:0000117 EHDAA2:0003117 http://www.xspan.org/obo.owl# A group of connected epithelial tubes with a single portal. AEO:JB epithelial plexus A network of interlinking epithelial tubes. AEO:0000118 EHDAA2:0003118 http://www.xspan.org/obo.owl# A network of interlinking epithelial tubes. AEO:JB epithelial vesicle A closed epithelium with a lumen. AEO:0000119f EHDAA2:0003119 http://www.xspan.org/obo.owl# A closed epithelium with a lumen. AEO:JB muscle tissue A tissue composed of myoblasts or muscle cells. AEO:0000122 EHDAA2:0003122 http://www.xspan.org/obo.owl# A tissue composed of myoblasts or muscle cells. AEO:JB neural tissue AEO:0000123 EHDAA2:0003123 Tissue composed predominantly of neurons. http://www.xspan.org/obo.owl# AEO:JB Tissue composed predominantly of neurons. developing anatomical structure A structure whose morphology or state of differentiation will change during normal development. AEO:0000125 EHDAA2:0003125 UBERON:0005423 http://www.xspan.org/obo.owl# A structure whose morphology or state of differentiation will change during normal development. AEO:JB larva A post-embryonic juvenile form which will undergo metamorphosis to become the adult. AEO:0000126 EHDAA2:0003126 http://www.xspan.org/obo.owl# A post-embryonic juvenile form which will undergo metamorphosis to become the adult. AEO:JB apoptosing developing anatomical entity AEO:0000127 An embryonic anatomical structure undergoing apoptosis. EHDAA2:0003127 http://www.xspan.org/obo.owl# AEO:JB An embryonic anatomical structure undergoing apoptosis. functioning and developing structure AEO:0000129 An embryonic entity that displays a physiological function but whose strucuture is not yet fully formed. EHDAA2:0003129 http://www.xspan.org/obo.owl# AEO:JB An embryonic entity that displays a physiological function but whose strucuture is not yet fully formed. developing structure with stem cells AEO:0000131 EHDAA2:0003131 Embronic structure that contains stem cellsr that may contribute to its future development or maintenance or to its future development or maintenance of another tissue. http://www.xspan.org/obo.owl# AEO:JB Embronic structure that contains stem cellsr that may contribute to its future development or maintenance or to its future development or maintenance of another tissue. transitional anatomical structure AEO:0000132 An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. EHDAA2:0003132 http://www.xspan.org/obo.owl# AEO:JB An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. ganglion A group of neurons, usually outside the CNS, which relay neuronal signals. AEO:0000135 EHDAA2:0003135 http://www.xspan.org/obo.owl# A group of neurons, usually outside the CNS, which relay neuronal signals. AEO:JB neuronal nucleus A localised domain of predominantly neuronal tissue in the central nervous system. AEO:0000136 EHDAA2:0003136 http://www.xspan.org/obo.owl# A localised domain of predominantly neuronal tissue in the central nervous system. AEO:JB nerve A group of neurons that provides a nervous supply. AEO:0000137 EHDAA2:0003137 http://www.xspan.org/obo.owl# A group of neurons that provides a nervous supply. AEO:JB nerve plexus A complex of interconnecting nerves. AEO:0000138 EHDAA2:0003138 http://www.xspan.org/obo.owl# A complex of interconnecting nerves. AEO:JB nerve fiber tract A fasciculated bundle of neuron projections, largely or completely lacking synapses. AEO:0000139 EHDAA2:0003139 http://www.xspan.org/obo.owl# neuron projection bundle GO:0043005 neuron projection bundle A fasciculated bundle of neuron projections, largely or completely lacking synapses. CARO:0001001 GO:0043005 striated muscle tissue A tissue composed of striated muscle cells. AEO:0000140 EHDAA2:0003140 http://www.xspan.org/obo.owl# A tissue composed of striated muscle cells. AEO:JB smooth muscle tissue A tissue composed of smooth muscle cells. AEO:0000141 EHDAA2:0003141 http://www.xspan.org/obo.owl# A tissue composed of smooth muscle cells. AEO:JB cardiac muscle tissue A tissue composed of cardiac muscle cells. AEO:0000142 EHDAA2:0003142 http://www.xspan.org/obo.owl# A tissue composed of cardiac muscle cells. AEO:JB smooth muscle sphincter A ring of smooth muscle cells whose contraction closes the opening of the ring. AEO:0000143 EHDAA2:0003143 http://www.xspan.org/obo.owl# A ring of smooth muscle cells whose contraction closes the opening of the ring. AEO:JB striated muscle sphincter A ring of striated muscle cells whose contraction closes the opening of the ring. AEO:0000144 EHDAA2:0003144 http://www.xspan.org/obo.owl# A ring of striated muscle cells whose contraction closes the opening of the ring. AEO:JB mesenchymal tissue A group of not-yet-terminally-differentiatied cells that can pack in three dimensions. AEO:0000145 EHDAA2:0003145 http://www.xspan.org/obo.owl# A group of not-yet-terminally-differentiatied cells that can pack in three dimensions. AEO:JB dense mesenchyme tissue AEO:0000146 EHDAA2:0003146 Mesenchyme with little extracellular matrix. http://www.xspan.org/obo.owl# AEO:JB Mesenchyme with little extracellular matrix. cartilagenous condensation AEO:0000147 Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. EHDAA2:0003147 http://www.xspan.org/obo.owl# AEO:JB Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. GO:curator VAO:0000092 developing mesenchymal condensation A delimited region of dense mesenchyme within looser mesenchyme. AEO:0000148 EHDAA2:0003148 http://www.xspan.org/obo.owl# A delimited region of dense mesenchyme within looser mesenchyme. AEO:JB pre-muscle condensation A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become myoblasts. AEO:0000149 EHDAA2:0003149 http://www.xspan.org/obo.owl# A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become myoblasts. AEO:JB pre-cartilage condensation A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. AEO:0000150 EHDAA2:0003150 http://www.xspan.org/obo.owl# A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. AEO:JB loose mesenchyme tissue AEO:0000151 EHDAA2:0003151 Mesenchyme whose cells are embedded in obvious amounts fo extracellular matrix. http://www.xspan.org/obo.owl# AEO:JB Mesenchyme whose cells are embedded in obvious amounts fo extracellular matrix. migrating mesenchyme population AEO:0000152 EHDAA2:0003152 Mesenchymal cells that are migrating. http://www.xspan.org/obo.owl# AEO:JB Mesenchymal cells that are migrating. mesenchymal tissue with stem cells AEO:0000153 EHDAA2:0003153 Multi-tissue mesenchymal structure one of whose parts contains stem cells that can replace other parts. http://www.xspan.org/obo.owl# AEO:JB Multi-tissue mesenchymal structure one of whose parts contains stem cells that can replace other parts. organism surfacef AEO:0000154 EHDAA2:0003154 The collection of structures that form the exxtenal covering of the organism. http://www.xspan.org/obo.owl# AEO:JB The collection of structures that form the exxtenal covering of the organism. groove A furrow or an incomplete tube. AEO:0000161 EHDAA2:0003161 UBERON:0006846 ZFA:0001690 http://www.xspan.org/obo.owl# A furrow or an incomplete tube. AEO:JB ridge A raised strip of tissue. AEO:0000162 EHDAA2:0003162 http://www.xspan.org/obo.owl# A raised strip of tissue. AEO:JB skeletal system AEO:0000168 EHDAA2:0003168 The rigid support system for the body. http://www.xspan.org/obo.owl# AEO:JB The rigid support system for the body. VAO:0000027 embryo AEO:0000169 EHDAA2:0003169 That part of the conceptus that will form the organism. UBERON:0000922 ZFA:0001105 http://www.xspan.org/obo.owl# AEO:JB That part of the conceptus that will form the organism. anlage AEO:0000170 Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. EHDAA2:0003170 http://www.xspan.org/obo.owl# AEO:JB Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. primordium AEO:0000171 EHDAA2:0003171 Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue. http://www.xspan.org/obo.owl# AEO:JB Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue. limb AEO:0000172 Appendage of an animal used for locomotion or grasping. EHDAA2:0003172 http://www.xspan.org/obo.owl# AEO:JB Appendage of an animal used for locomotion or grasping. surface sense organ AEO:0000173 EHDAA2:0003173 Multicellular anatomical structure with largely bona fide boundary that extends outwards from or is part of the organism surface and transduces some sensory stimulus to the nervous system. http://www.xspan.org/obo.owl# AEO:JB Multicellular anatomical structure with largely bona fide boundary that extends outwards from or is part of the organism surface and transduces some sensory stimulus to the nervous system. gender-specific anatomical structure A part of the body present only in a specific gender. AEO:0000174 EHDAA2:0003174 http://www.xspan.org/obo.owl# A part of the body present only in a specific gender. AEO:JB male anatomical structure A part of the body present only in males. AEO:0000175 EHDAA2:0003175 http://www.xspan.org/obo.owl# A part of the body present only in males. AEO:JB female anatomical structure A part of the body present only in females. AEO:0000176 EHDAA2:0003176 http://www.xspan.org/obo.owl# A part of the body present only in females. AEO:JB hermaphrodite anatomical structure A part of the body present only in hermaphrodites. AEO:0000177 EHDAA2:0003177 http://www.xspan.org/obo.owl# A part of the body present only in hermaphrodites. AEO:JB fibrous joint A flexible joint between two bones that is made of unossified connective tissue. AEO:0000178 EHDAA2:0003178 http://www.xspan.org/obo.owl# A flexible joint between two bones that is made of unossified connective tissue. AEO:JB joint-associated cartilage AEO:0000179 EHDAA2:0003179 The articular cartilage covering of the region of bone within a synoval joint. http://www.xspan.org/obo.owl# AEO:JB The articular cartilage covering of the region of bone within a synoval joint. non-joint-associated cartilage AEO:0000180 Cartilage that may provide the template for an endochondral bone or that may be a disinct entity in the skeleton. EHDAA2:0003180 http://www.xspan.org/obo.owl# AEO:JB Cartilage that may provide the template for an endochondral bone or that may be a disinct entity in the skeleton. synovial membrane AEO:0000181 EHDAA2:0003181 The epithelial membrane between bone ends that forms the lateral borders of the synovial cavity and secretes synovial fluid. http://www.xspan.org/obo.owl# AEO:JB The epithelial membrane between bone ends that forms the lateral borders of the synovial cavity and secretes synovial fluid. synovial joint A joint connecting two or more bones with cartilage at the bone ends and a synovial membrane that secretes synovial fluid conecting the bones and sealing the synovial cavity. AEO:0000183 EHDAA2:0003183 http://www.xspan.org/obo.owl# A joint connecting two or more bones with cartilage at the bone ends and a synovial membrane that secretes synovial fluid conecting the bones and sealing the synovial cavity. AEO:JB exoskeletal tissue A component of the exoskeleton. AEO:0000185 EHDAA2:0003185 http://www.xspan.org/obo.owl# A component of the exoskeleton. AEO:JB body cavity AEO:0000186 EHDAA2:0003186 The cavity within the body that contains the visceral organs. UBERON:0002323 http://www.xspan.org/obo.owl# AEO:JB The cavity within the body that contains the visceral organs. multi-tissue structure with stem cells AEO:0000187 EHDAA2:0003187 Multi-tissue structure one of whose parts contains stem cells that can replace other parts. http://www.xspan.org/obo.owl# AEO:JB Multi-tissue structure one of whose parts contains stem cells that can replace other parts. acellular fluid anatomical entity AEO:0000188 An acellular fluid portion of organism substance that is produced by the organism for some non-waste purpose. EHDAA2:0003188 http://www.xspan.org/obo.owl# AEO:JB An acellular fluid portion of organism substance that is produced by the organism for some non-waste purpose. epithelial tissue with stem cells AEO:0000189 EHDAA2:0003189 Multi-tissue epithelial structure one of whose parts contains stem cells that can replace other parts. http://www.xspan.org/obo.owl# AEO:JB Multi-tissue epithelial structure one of whose parts contains stem cells that can replace other parts. anatomical surface feature AEO:0000192 EHDAA2:0003010 Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures. anatomical surface. http://www.xspan.org/obo.owl# true CARO:MAH Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures. appendage AEO:0000193 EHDAA2:0003193 Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified]. An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs. UBERON:0000026 http://www.xspan.org/obo.owl# CARO:MAH Organ or organ part that is attached to the body of an organism. For example a limb[GO, modified]. An appendage is an external body part, or natural prolongation, that protrudes from an organism's body, such as a vertebrate's limbs. conceptus AEO:0000194 All the products of the fertilized egg. EHDAA2:0003205 http://www.xspan.org/obo.owl# AEO:JB All the products of the fertilized egg. extraembryonic component AEO:0000195 The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. http://www.xspan.org/obo.owl# AEO:JB The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. larval anatomical structure AEO:0000196 An anatomical structure present in the larval form of an animal. HDAA2:0003126 http://www.xspan.org/obo.owl# AEO:JB An anatomical structure present in the larval form of an animal. antenna A head-associated surface sense organ. AEO:0000198 http://www.xspan.org/obo.owl# A head-associated surface sense organ. CARO:MAH mucous membrane A membranous structure with more than one cell type, one or more of which secretes mucus, that lines body passages which communicate with the exterior. AEO:0000199 EHDAA2:0003234 http://www.xspan.org/obo.owl# mucosa A membranous structure with more than one cell type, one or more of which secretes mucus, that lines body passages which communicate with the exterior. AEO:JB regenerating anatomical structure AEO:0000200 An anatomical structure that, as part of its normal physiology, undergoes regeneration. Examples include endometrium and antlers. EHDAA2:0003233 http://www.xspan.org/obo.owl# AEO:JB An anatomical structure that, as part of its normal physiology, undergoes regeneration. Examples include endometrium and antlers. afferent nerve A group of neurons that provides a nervous response from a tissue. AEO:0000201 EHDAA2:0003200 http://www.xspan.org/obo.owl# A group of neurons that provides a nervous response from a tissue. AEO:JB efferent nerve A group of neurons that provides a nervous signal to a tissue. AEO:0000202 EHDAA2:0003231 http://www.xspan.org/obo.owl# A group of neurons that provides a nervous signal to a tissue. AEO:JB syncytium AEO:0000203 An anatomical entity consisting of a single or a few multinucleated structures. HDAA2:0003248 http://www.xspan.org/obo.owl# AEO.:JB An anatomical entity consisting of a single or a few multinucleated structures. pit AEO:0000204 An roughly circular indentation in a surface. EHDAA2:003249 http://www.xspan.org/obo.owl# AEO:JB An roughly circular indentation in a surface. protuberance A roughly circular bulge in a surface. AEO:0000205 EHDAA2:0003250 http://www.xspan.org/obo.owl# A roughly circular bulge in a surface. AEO:JB migrating epithelium AEO:0000206 An epithelium that extends its surface area by peripheral movement. EHDAA2:0003251 http://www.xspan.org/obo.owl# AEO:JB An epithelium that extends its surface area by peripheral movement. blood vessel AEO:0000207 An epithelial tube that transports blood. EHDAA2:0003252 http://www.xspan.org/obo.owl# AEO:JB An epithelial tube that transports blood. artery AEO:0000208 An epithelial tube that transports blood away from the heart. EHDAA2:0003253 http://www.xspan.org/obo.owl# AEO:JB An epithelial tube that transports blood away from the heart. vein AEO:0000209 An epithelial tube that transports blood towards the heart. EHDAA2:0003254 http://www.xspan.org/obo.owl# AEO:JB An epithelial tube that transports blood towards the heart. row AEO:0000210 Anatomical group whose component structures are arranged in a row. FBbt:00100152 HDAA2:0003255 http://www.xspan.org/obo.owl# Anatomical group whose component structures are arranged in a row. DBft:DOS non-connected developing functional system AEO:0000211 FBbt:0004003 HDAA2:0003256 The sum of all the anlagen and primordia that will develop into a single functional system. http://www.xspan.org/obo.owl# FBbt:DOS The sum of all the anlagen and primordia that will develop into a single functional system. sclerotome AEO:0000212 EHDAA2:0003257 The mesenchymal derivative of a somite that will migrate to surround the neural tube and form vertebrae. http://www.xspan.org/obo.owl# AEO:JB The mesenchymal derivative of a somite that will migrate to surround the neural tube and form vertebrae. bone condensation A delimited region of osteoblasts representing the early stages of bone formation. AEO:0000213 EHDAA2:0003258 http://www.xspan.org/obo.owl# A delimited region of osteoblasts representing the early stages of bone formation. AEO:JB dermomyotome AEO:0000214 EHDAA2:0003259 The bilaminar epithelium formed from the myotome and dermatome. http://www.xspan.org/obo.owl# AEO:JB The bilaminar epithelium formed from the myotome and dermatome. open cavity A volume that is mainly bounded but has an opening to another cavity or to the outside. AEO:0000215 EHDAA2:0003078 http://www.xspan.org/obo.owl# A volume that is mainly bounded but has an opening to another cavity or to the outside. JB:AEO epithelial cord A cord of epithelial cells without a lumen and usually several cells thick. AEO:0000216 EHDAA2:0004052 http://www.xspan.org/obo.owl# A cord of epithelial cells without a lumen and usually several cells thick. JB:AEO migrating developing tissue A simple coherent tissue or a localized population of similar cells that are actively migrating. AEO:0000217 EHDAA2:0004053 http://www.xspan.org/obo.owl# A simple coherent tissue or a localized population of similar cells that are actively migrating. JB:AEO developing epithelial placode A domain of columnar epithelium in an embryo that represents the early stage of the development of the epithelial component of a new anatomical structure. AEO:0000218 EHDAA2:0003112 http://www.xspan.org/obo.owl# A domain of columnar epithelium in an embryo that represents the early stage of the development of the epithelial component of a new anatomical structure. JB:AEO vascular plexus A network of interlinked veins. AEO:0000219 EHDAA2:0004112 http://www.xspan.org/obo.owl# A network of interlinked veins. JB:AEO tooth AEO:0000220 EHDAA2:0004605 Each of a set of hard, bony enamel-coated structures in the jaws of most vertebrates, used for biting and chewing. http://www.xspan.org/obo.owl# Each of a set of hard, bony enamel-coated structures in the jaws of most vertebrates, used for biting and chewing. JB:AEO open anatomical space AEO:0000221 An anatomical space with at least one opening to another space or the exterior. http://www.xspan.org/obo.owl# An anatomical space with at least one opening to another space or the exterior. JB:AEO enclosed anatomical space AEO:0000222 An anatomical space with no opening to another space or to the exterior. http://www.xspan.org/obo.owl# An anatomical space with no opening to another space or to the exterior. JB:AEO fat tissue AEO:0000493 EHDAA2:0003120 Tissue that is predominantly made of fat cells. http://www.xspan.org/obo.owl# AEO:JB Tissue that is predominantly made of fat cells. sensory ganglion A ganglion containing sensory neurons. AEO:0001000 http://www.xspan.org/obo.owl# A ganglion containing sensory neurons. JB:AEO autonomic ganglion A ganglion that is part of the autonomic nervous system. AEO:0001001 http://www.xspan.org/obo.owl# A ganglion that is part of the autonomic nervous system. JB:AEO capillary bed A localized group of blood capillaries. AEO:0001002 http://www.xspan.org/obo.owl# A localized group of blood capillaries. JB:AEO acellular extracellular matrix AEO:0001003 An acellular structure typically composed of collagen, glycoproteins and glycosaminoglycans. http://www.xspan.org/obo.owl# An acellular structure typically composed of collagen, glycoproteins and glycosaminoglycans. JB:AEO fin A flattened appendage on a marine animal. AEO:0001004 http://www.xspan.org/obo.owl# A flattened appendage on a marine animal. JB:AEO VAO:0000099 secretion A non-cellular substance released by a cell, gland or tissue. AEO:0001005 UBERON:0000456 http://www.xspan.org/obo.owl# A non-cellular substance released by a cell, gland or tissue. JB:AEO excreta AEO:0001006 Excreta are bodily fluids consisting of waste matter, such as sweat or feces, discharged from the body. UBERON:0000174 http://www.xspan.org/obo.owl# Excreta are bodily fluids consisting of waste matter, such as sweat or feces, discharged from the body. JB:AEO developing epithelium AEO:0001007 An epithelium within an embryo or larva that is undergoing a major developmental change. EHDAA2:0004653 http://www.xspan.org/obo.owl# AEO:JB An epithelium within an embryo or larva that is undergoing a major developmental change. neuroepithelium AEO:0001008 An embryonic or larval epithelium that is committed to form part of the nervous system. EHDAA2:0004654 http://www.xspan.org/obo.owl# AEO:JB An embryonic or larval epithelium that is committed to form part of the nervous system. proliferating neuroepithelium AEO:0001009 An epithelium that is undergoing proliferation to provide large numbers of neuronal cells. EHDAA2:0004655 http://www.xspan.org/obo.owl# AEO:JB An epithelium that is undergoing proliferation to provide large numbers of neuronal cells. differentiating neuroepithelium A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells. AEO:0001010 EHDAA2:0004656 http://www.xspan.org/obo.owl# A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells. AEO:JB neuronal white matter AEO:0001011 EHDAA2:0004657 Neuronal tissue composed predominantly of axons. http://www.xspan.org/obo.owl# AEO:JB Neuronal tissue composed predominantly of axons. neuronal grey matter A neuronal tissue composed predominantly of nerve bodies and neuronal support cells. AEO:0001012 EHDAA2:0004658 http://www.xspan.org/obo.owl# A neuronal tissue composed predominantly of nerve bodies and neuronal support cells. AEO:JB neuronal column AEO:0001013 An extended columnar domain of predominantly neuronal tissue in the central nervous system. EHDAA2:0004659 http://www.xspan.org/obo.owl# AEO:JB An extended columnar domain of predominantly neuronal tissue in the central nervous system. differentiating neuronal condensation A compact group of cells differentiating to become a ganglion or a neuronal nucleus. AEO:0001014 EHDAA2:0004660 http://www.xspan.org/obo.owl# A compact group of cells differentiating to become a ganglion or a neuronal nucleus. AEO:JB somite AEO:0001015 An epithelial ball that forms from paraxial mesoderm. http://www.xspan.org/obo.owl# An epithelial ball that forms from paraxial mesoderm. JB:AEO developing mesenchymal structure A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. AEO:0001016 http://www.xspan.org/obo.owl# A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. AEO:JB dermatome A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. AEO:0001017 http://www.xspan.org/obo.owl# A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. AEO:JB myotome A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. AEO:0001018 http://www.xspan.org/obo.owl# A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. AEO:JB developing germ cell population A germ cell population that has not undergone meiosis. AEO:0001019 http://www.xspan.org/obo.owl# A germ cell population that has not undergone meiosis. AEO:JB reproductive cell population A population of cells that are predominantly immature or mature germ cells. AEO:0001020 http://www.xspan.org/obo.owl# A population of cells that are predominantly immature or mature germ cells. AEO:JB stem cell population A group of cells capable of regenerating themselves and also of producing one or more populations of differentiated cells. AEO:0001021 http://www.xspan.org/obo.owl# A group of cells capable of regenerating themselves and also of producing one or more populations of differentiated cells. AEO:JB anatomical entity Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. CARO:0000000 EHDAA2:0003000 UBERON:0001062 http://www.xspan.org/obo.owl# Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. CARO:MAH anatomical structure CARO:0000003 EHDAA2:0003003 Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome. UBERON:0000061 http://www.xspan.org/obo.owl# CARO:MAH Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome. non-tissue substance CARO:0000004 EHDAA2:0003004 Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. UBERON:0000463 http://www.xspan.org/obo.owl# portion of organism substance CARO:MAH Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. anatomical space CARO:0000005 EHDAA2:0003005 Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. UBERON:0000464 http://www.xspan.org/obo.owl# CARO:MAH Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. material anatomical entity Anatomical entity that has mass. CARO:0000006 EHDAA2:0003006 UBERON:0000465 http://www.xspan.org/obo.owl# Anatomical entity that has mass. CARO:MAH immaterial anatomical entity Anatomical entity that has no mass. CARO:0000007 EHDAA2:0003007 UBERON:0000466 http://www.xspan.org/obo.owl# Anatomical entity that has no mass. CARO:MAH anatomical line CARO:0000008 EHDAA2:0003008 Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface. http://www.xspan.org/obo.owl# CARO:MAH Non-material anatomical entity of one dimension, which forms a boundary of an anatomical surface or is a modulation of an anatomical surface. anatomical point CARO:0000009 EHDAA2:0003009 Non-material anatomical entity of zero dimension, which forms a boundary of an anatomical line or surface. http://www.xspan.org/obo.owl# CARO:MAH Non-material anatomical entity of zero dimension, which forms a boundary of an anatomical line or surface. anatomical surface CARO:0000010 EHDAA2:0003192 Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures. UBERON:0000015 http://www.xspan.org/obo.owl# CARO:MAH Non-material anatomical entity of two dimensions, that is demarcated by anatomical lines or points on the external or internal surfaces of anatomical structures. anatomical system Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity. CARO:0000011 EHDAA2:0003011 http://www.xspan.org/obo.owl# Anatomical group that is has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity. CARO:MAH multi-cellular organism Anatomical structure that is an individual member of a species and consists of more than one cell. CARO:0000012 EHDAA2:0003191 UBERON:0000468 http://www.xspan.org/obo.owl# Anatomical structure that is an individual member of a species and consists of more than one cell. JB:DEF cell Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CARO:0000013 http://www.xspan.org/obo.owl# Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CARO:MAH cell component Anatomical structure that is a direct part of the cell. CARO:0000014 http://www.xspan.org/obo.owl# Anatomical structure that is a direct part of the cell. CARO:MAH compound organ component CARO:0000019 EHDAA2:0003019 Multi-tissue structure that is part of a compound organ. http://www.xspan.org/obo.owl# CARO:MAH Multi-tissue structure that is part of a compound organ. simple organ CARO:0000021 EHDAA2:0003190 Multi-tissue structure that is not part of a compound organ. http://www.xspan.org/obo.owl# CARO:MAH Multi-tissue structure that is not part of a compound organ. compound organ Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. CARO:0000024 EHDAA2:0003024 http://www.xspan.org/obo.owl# Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. CARO:MAH male organism CARO:0000027 Gonochoristic organism that can produce male gametes. http://www.xspan.org/obo.owl# CARO:MAH Gonochoristic organism that can produce male gametes. female organism CARO:0000028 Gonochoristic organism that can produce female gametes. http://www.xspan.org/obo.owl# CARO:MAH Gonochoristic organism that can produce female gametes. hermaphroditic organism CARO:0000029 Multi-cellular organism that can produce both male and female gametes. dioecious organism http://www.xspan.org/obo.owl# CARO:MAH Multi-cellular organism that can produce both male and female gametes. organism subdivision Anatomical structure which is a primary subdivision of whole organism. The mereological sum of these is the whole organism. CARO:0000032 EHDAA2:0003032 UBERON:0000475 http://www.xspan.org/obo.owl# Anatomical structure which is a primary subdivision of whole organism. The mereological sum of these is the whole organism. CARO:MAH acellular anatomical structure Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. CARO:0000040 EHDAA2:0003040 UBERON:0000476 http://www.xspan.org/obo.owl# Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. CARO:MAH anatomical cluster Anatomical group that has its parts adjacent to one another. Anatomical structure, which has as its parts a heterogeneous collection of organs, organ parts, cells or body part subdivisions that are adjacent to, or continuous with one another; does not constitute an organ, organ system or organ system subdivision, or body part or body part subdivision. CARO:0000041 EHDAA2:0003041 UBERON:0000477 http://www.xspan.org/obo.owl# Anatomical group that has its parts adjacent to one another. Anatomical structure, which has as its parts a heterogeneous collection of organs, organ parts, cells or body part subdivisions that are adjacent to, or continuous with one another; does not constitute an organ, organ system or organ system subdivision, or body part or body part subdivision. CARO:MAH extraembryonic structure Anatomical structure that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo. CARO:0000042 EHDAA2:0003042 UBERON:0000478 http://www.xspan.org/obo.owl# Anatomical structure that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo. CARO:MAH simple tissue Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships. CARO:0000043 EHDAA2:0003043 UBERON:0000479 http://www.xspan.org/obo.owl# portion of tissue. Anatomical structure, that consists of similar cells and intercellular matrix, aggregated according to genetically determined spatial relationships. CARO:MAH sequential hermaphroditic organism CARO:0000045 Hermaphroditic organism that produces gametes first of one sex, and then later of the other sex. consecutive hermaphroditic organism http://www.xspan.org/obo.owl# CARO:MAH Hermaphroditic organism that produces gametes first of one sex, and then later of the other sex. synchronous hermaphroditic organism CARO:0000046 Hermaphroditic organism that produces both male and female gametes at the same time. http://www.xspan.org/obo.owl# serially hermaphroditic organism CARO:MAH Hermaphroditic organism that produces both male and female gametes at the same time. gonochoristic organism CARO:0000048 Multi-cellular organism that has male and female sexes. http://www.xspan.org/obo.owl# monoecious organism CARO:MAH Multi-cellular organism that has male and female sexes. protandrous hermaphroditic organism CARO:0000049 Sequential hermaphroditic organism that produces gametes first of the male sex, and then later of the female sex. http://www.xspan.org/obo.owl# CARO:MAH Sequential hermaphroditic organism that produces gametes first of the male sex, and then later of the female sex. protogynous hermaphroditic organism CARO:0000050 Sequential hermaphroditic organism that produces gametes first of the female sex, and then later of the male sex. http://www.xspan.org/obo.owl# CARO:MAH Sequential hermaphroditic organism that produces gametes first of the female sex, and then later of the male sex. anatomical group Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue. CARO:0000054 EHDAA2:0003054 UBERON:0000480 http://www.xspan.org/obo.owl# Anatomical structure consisting of at least two non-overlapping organs, multi-tissue aggregates or portion of tissues or cells of different types that does not constitute an organism, organ, multi-tissue aggregate, or portion of tissue. CARO:MAH multi-tissue structure Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. CARO:0000055 EHDAA2:0003055 UBERON:0000481 http://www.xspan.org/obo.owl# Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. CARO:MAH cell space Anatomical space that is part of a cell. CARO:0000062 http://www.xspan.org/obo.owl# Anatomical space that is part of a cell. CARO:mah asexual organism CARO:0000063 Multi-cellular organism that does not produce gametes. http://www.xspan.org/obo.owl# CARO:MAH Multi-cellular organism that does not produce gametes. single cell organism CARO:0000064 Cell that is an individual member of a species. http://www.xspan.org/obo.owl# CARO:MAH Cell that is an individual member of a species. basal lamina Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue. CARO:0000065 EHDAA2:0003065 http://www.xspan.org/obo.owl# Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue. CARO:MAH epithelium CARO:0000066 EHDAA2:0003066 Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. http://www.xspan.org/obo.owl# CARO:MAH Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. simple cuboidal epithelium CARO:0000067 EHDAA2:0003067 Unilaminar epithelium that consists of a single layer of cuboidal cells. http://www.xspan.org/obo.owl# CARO:MAH Unilaminar epithelium that consists of a single layer of cuboidal cells. columnar epithelium CARO:0000068 EHDAA2:0003068 Unilaminar epithelium that consists of a single layer of columnar cells. http://www.xspan.org/obo.owl# CARO:MAH Unilaminar epithelium that consists of a single layer of columnar cells. multilaminar epithelium CARO:0000069 EHDAA2:0003069 Epithelium that consists of more than one layer of epithelial cells. http://www.xspan.org/obo.owl# CARO:MAH Epithelium that consists of more than one layer of epithelial cells. simple squamous epithelium CARO:0000070 EHDAA2:0003070 Unilaminar epithelium that consists of a single layer of squamous cells. http://www.xspan.org/obo.owl# CARO:MAH Unilaminar epithelium that consists of a single layer of squamous cells. atypical epithelium CARO:0000071 EHDAA2:0003071 Epithelium that consists of epithelial cells not arranged in one ore more layers. http://www.xspan.org/obo.owl# CARO:MAH Epithelium that consists of epithelial cells not arranged in one ore more layers. cavitated compound organ CARO:0000072 Compound organ that contains one or more macroscopic anatomical spaces. EHDAA2:0003072 http://www.xspan.org/obo.owl# CARO:MAH Compound organ that contains one or more macroscopic anatomical spaces. unilaminar epithelium CARO:0000073 EHDAA2:0003073 Epithelium that consists of a single layer of epithelial cells. http://www.xspan.org/obo.owl# CARO:MAH Epithelium that consists of a single layer of epithelial cells. solid compound organ CARO:0000074 Compound organ that does not contain macroscopic anatomical spaces. EHDAA2:0003074 http://www.xspan.org/obo.owl# CARO:MAH Compound organ that does not contain macroscopic anatomical spaces. epithelial cell CARO:0000077 Cell which has as its part a cytoskeleton that allows for tight cell to cell contact and which has apical-basal cell polarity. http://www.xspan.org/obo.owl# CARO:MAH CL:0000066 Cell which has as its part a cytoskeleton that allows for tight cell to cell contact and which has apical-basal cell polarity. cell Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CL:0000000 cell Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. CARO:mah cell in vivo CL:0000003 cell cell by class CL:0000012 cell male germ cell A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte. CL:0000015 cell nurse cell A germline cell that contributes to the development of the oocyte by transferring cytoplasm directly to oocyte. GOC:tfm PMID:15848391 female germ cell CL:0000021 Female germ cell is a germ cell that supports female gamete production. cell Female germ cell is a germ cell that supports female gamete production. GOC:tfm PMID:11023867 PMID:20454446 neuron neural crest derived CL:0000029 cell neuroblast CL:0000031 cell stem cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. CL:0000034 cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. GOC:tfm MESH:A.11.872 germ line cell A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. CL:0000039 Originally this term had some plant germ line cell children cell A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. GOC:tfm ISBN:0721662544 non-terminally differentiated cell A precursor cell with a limited number of potential fates. CL:0000055 blast cell cell A precursor cell with a limited number of potential fates. SANBI:mhl fibroblast A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. CL:0000057 cell A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. ISBN:0517223651 MESH:A.11.329.228 http://63.198.234.228/OpenFMA/Fibroblast.html chondroblast An immature cartilage-producing cell found in growing cartilage. CL:0000058 cell chrondoplast An immature cartilage-producing cell found in growing cartilage. GOC:tfm ISBN:0618947256 osteoblast A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. CL:0000062 cell A bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. MESH:A.11.329.629 cell by histology A classification of cells by their microscopic appearance. CL:0000063 cell A classification of cells by their microscopic appearance. FB:ma GOC:tfm epithelial cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. CL:0000066 Epitheliocyte cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. FB:ma GOC:tfm MESH:A.11.436 duct epithelial cell CL:0000068 cell blood vessel endothelial cell An endothelial cell that lines the vasculature. CL:0000071 Cuboidal endothelial cell of vascular tree cell An endothelial cell that lines the vasculature. GOC:tfm columnar/cuboidal epithelial cell CL:0000075 cell squamous epithelial cell CL:0000076 cell stratified epithelial cell CL:0000079 cell circulating cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. CL:0000080 cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. GOC:add blood cell A cell found predominately in the blood. CL:0000081 cell A cell found predominately in the blood. GOC:add GOC:tfm neuron associated cell CL:0000095 cell interneuron CL:0000099 Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. cell GOC:tfm MESH:A.08.663.358 Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. sensory neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. CL:0000101 cell Any neuron having a sensory function; an afferent neuron conveying sensory impulses. ISBN:0721662544 autonomic neuron A neruon whose cell body is within an autonomic ganglion. CL:0000107 cell A neruon whose cell body is within an autonomic ganglion. GOC:tfm glial cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. CL:0000125 cell neuroglia neuroglial cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. MESH:A.08.637 macroglial cell A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. CL:0000126 Macrogliocyte cell A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. GOC:tfm ISBN:0721662544 astrocyte A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. CL:0000127 astrocytic glia cell A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. GOC:_tfm GOC:dsd MESH:A.08.637.200 MESH:D001253 PMID:11746784 PMID:12162730 PMID:12898703 PMID:20942978 oligodendrocyte A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. CL:0000128 cell oligodendroglia A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. MESH:A.08.637.600 microglial cell A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. CL:0000129 MF.microglia.CNS brain macrophage brain-resident macrophage cell hortega cells microglia microgliocyte http://www.copewithcytokines.de/ microgliocyte hortega cells http://www.copewithcytokines.de/ A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. GOC:add GOC:dsd GOC:tfm ISBN:0721601464 MESH:D017628 PMID:11517395 PMID:12430718 PMID:14561199 PMID:14612429 PMID:16177057 PMID:19461673 PMID:2089275 mesenchymal cell A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. BMSC CFU-F CL:0000134 CL:0002452 MSC Stem Cells, Mesenchymal bone marrow stromal cells cell colony-forming unit-fibroblast marrow stromal cells mesenchymal precursor cell mesenchymal progenitor cells mesenchymal stem cell mesenchymal stromal cell mesenchymal stromal cells MESH:D044982 mesenchymal progenitor cells MSC PMID:11378515 PMID:11378515 marrow stromal cells MESH:D044982 Stem Cells, Mesenchymal A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. FB:ma GOC:dsd PMCID:PMC2613570 PMID:10102814j PMID:16923606 PMID:_17986482 PMID:_19960544 http://en.wikipedia.org/wiki/Mesenchymal_stem_cell http://www.copewithcytokines.de/cope.cgi?key=mesenchymal%20stem%20cells fat cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. CL:0000136 CL:0000450 adipocyte adipose cell cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. MESH:A.11.329.114 chondrocyte CL:0000138 Polymorphic cell that form cartilage. cartilage cell cell MESH:A.11.329.171 Polymorphic cell that form cartilage. cell by function A classification of cells by their primary end goal or behavior. CL:0000144 cell A classification of cells by their primary end goal or behavior. FB:ma secretory cell A cell that specializes in controlled release of one or more substances. CL:0000151 cell A cell that specializes in controlled release of one or more substances. GOC:tfm ISBN:0721662544 neuroendocrine cell An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals. CL:0000165 cell neurosecretory cell An endocrine cell that has the specialized function to produce and secrete hormones in response to neuronal signals. MESH:A.06.688 muscle cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. CL:0000187 cell myocyte A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. MESH:A.11.620 skeletal muscle cell A somatic cell located in skeletal muscle. CL:0000188 cell A somatic cell located in skeletal muscle. GOC:tfm smooth muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). CL:0000191 CL:0000192 SMCs cell myocytes, smooth muscle non-striated muscle cell smooth muscle fiber MESH:D032389 myocytes, smooth muscle PMID:9315361 SMCs A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). MESH:A.11.620.520 MESH:D032389 PMID:9315361 flight muscle cell CL:0000196 cell electrically active cell A cell whose function is determined by the generation or the reception of an electric signal. CL:0000211 cell A cell whose function is determined by the generation or the reception of an electric signal. FB:ma cell by nuclear number A classification of cells by the number of their nuclei. CL:0000224 cell A classification of cells by the number of their nuclei. FB:ma GOC:tfm multinucleate cell A cell with more than one nucleus. CL:0000228 cell syncitium syncytial cell syncytium A cell with more than one nucleus. FB:ma glial cell (sensu Vertebrata) A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. CL:0000243 cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Form the myelin insulation of nervous pathways, guide neuronal migration during development, and exchange metabolites with neurons. Neuroglia have high-affinity transmitter uptake systems, voltage-dependent and transmitter-gated ion channels, and can release transmitters, but their role in signaling (as in many other functions) is unclear. MESH:A.08.637 extracellular matrix secreting cell CL:0000327 cell mesenchyme condensation cell A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. CL:0000335 cell A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. GOC:tfm PMID:5025404 electrically responsive cell A cell whose function is determined by its response to an electric signal. CL:0000393 cell A cell whose function is determined by its response to an electric signal. FB:ma cell by ploidy A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei. CL:0000414 cell A classification of cells by the number of haploid genome equivalents of their nucleus or nuclei. FB:ma GOC:tfm obliquely striated muscle cell CL:0000444 cell apoptosis fated cell CL:0000445 cell neuroglioblast CL:0000468 cell stromal cell A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. CL:0000499 cell A connective tissue cell of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the hematopoietic system and elsewhere. GOC:tfm MESH:A.11.329.830 syncytiotrophoblast cell A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. CL:0000525 cell plasmidotrophoblast syncytial trophoblast syntrophoblast A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo. It It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. GOC:tfm ISBN:0323052908 afferent neuron A neuron which conveys sensory information centrally from the periphery. CL:0000526 cell input neuron A neuron which conveys sensory information centrally from the periphery. GOC:tfm MESH:A.08.663.650 efferent neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. CL:0000527 cell output neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. MESH:A.08.663.655 neuron CL:0000540 The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. cell nerve cell MESH:A.08.663 MESH:D009474 The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. germ cell CL:0000586 The reproductive cell in multicellular organisms. cell MESH:A.05.360.490 The reproductive cell in multicellular organisms. cuticle secreting cell An epithelial cell that secretes cuticle. CL:0000658 cell An epithelial cell that secretes cuticle. GOC:tfm collagen secreting cell An extracellular matrix secreting cell that secretes collagen. CL:0000667 cell An extracellular matrix secreting cell that secretes collagen. GOC:tfm primordial germ cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. CL:0000670 Gonocyte Primitive germ cell cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. GOC:tfm PMID:1381289 muscle precursor cell CL:0000680 cell striated muscle cell CL:0000737 Muscle cell which has as its direct parts myofilaments organized into sarcomeres. cell GOC:tfm ISBN:0721662544 Muscle cell which has as its direct parts myofilaments organized into sarcomeres. cardiac muscle cell A myocyte located in the heart. The contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. CL:0000746 cardiac myocyte cardiocyte cardiomyocyte cell heart muscle cell A myocyte located in the heart. The contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. GOC:tfm ISBN:0323052908 hematopoietic cell A cell of a hematopoietic lineage. CL:0000988 cell haematopoietic cell haemopoietic cell hemopoietic cell A cell of a hematopoietic lineage. GOC:add GO_REF:0000031 nucleate cell A cell containing at least one nucleus. CL:0002242 cell A cell containing at least one nucleus. GOC:tfm neural cell A cell that is part of the nervous system. CL:0002319 cell A cell that is part of the nervous system. GOC:tfm ISBN:0618947256 connective tissue cell A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. CL:0002320 CL:1000406 cell A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. GOC:tfm ISBN:0618947256 somatic cell A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). CL:0002371 cell A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). GOC:tfm ISBN:0721662544 myotube A myotube is a multinucleated cells that is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. CL:0000369 CL:0002372 cell myotubule single cell sarcomere skeletal muscle fiber A myotube is a multinucleated cells that is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. GOC:tfm ISBN:0323052908 Schwann cell A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function. CL:0002573 cell A glial cell that ensheathes axons of neuron in the peripheral nervous system and are necessary for their maintainance and function. GOC:tfm