@prefix dce: <http://purl.org/dc/elements/1.1/>.
@prefix owl: <http://www.w3.org/2002/07/owl#>.
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#>.
@prefix skos: <http://www.w3.org/2004/02/skos/core#>.
@prefix event: <http://eulersharp.sourceforge.net/2003/03swap/event#>.
@prefix humanbody: <http://eulersharp.sourceforge.net/2003/03swap/humanBody#>.
@prefix clinobs: <http://www.agfa.com/w3c/2009/clinicalObservation#>.
@prefix clisko: <http://www.agfa.com/w3c/2009/clinicalSKOSSchemes#>.
@prefix humdis: <http://www.agfa.com/w3c/2009/humanDisorder#>.
@prefix morph: <http://www.agfa.com/w3c/2009/clinicalMorphology#>.

<http://www.agfa.com/w3c/2009/clinicalMorphology>
	a owl:Ontology;
	dce:title """Clinical Morphology"""@en;
	dce:creator """Hans Cools, MD, Agfa Healthcare/Belgium"""@en;
	dce:contributor """Until 2010: Pieterjan De Potter, Ghent University - IBBT/ELIS - Multimedia Lab/Belgium"""@en;
	dce:publisher """Agfa Healthcare/Belgium"""@en;
	dce:description """Formal description of altered human morphology."""@en;
	dce:format """OWL Full"""@en;
	rdfs:comment """Copyright (c) 2009 Agfa-Gevaert Group and Ghent University - IBBT/ELIS - Multimedia Lab. All Rights Reserved. THIS IS UNPUBLISHED PROPRIETARY SOURCE CODE OF Agfa-Gevaert Group and Ghent University - IBBT/ELIS - Multimedia Lab The copyright notice above does not evidence any actual or intended publication of such source code."""@en.

#
# CLASSES
#

morph:MorphologicallyAlteredStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """morphologically altered structure"""@en;
	rdfs:subClassOf humanbody:AcquiredStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "118956008"^^clisko:sct20080731DT].

morph:MorphologicallyAbnormalStructure
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """morphologically abnormal structure"""@en;
	rdfs:subClassOf morph:MorphologicallyAlteredStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "49755003"^^clisko:sct20080731DT].

morph:MechanicalAbnormality
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """mechanical abnormality"""@en;
	rdfs:subClassOf morph:MorphologicallyAbnormalStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "107658001"^^clisko:sct20080731DT].

morph:Dilatation
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """dilatation"""@en;
	rdfs:subClassOf morph:MechanicalAbnormality;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "25322007"^^clisko:sct20080731DT].

morph:FluidDisturbance
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """fluid disturbance"""@en;
	rdfs:subClassOf morph:MechanicalAbnormality;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "107666005"^^clisko:sct20080731DT].
	
morph:Edema
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """edema"""@en;
	rdfs:subClassOf morph:FluidDisturbance;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "79654002"^^clisko:sct20080731DT].

morph:PeripheralEdema
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """peripheral edema"""@en;
	rdfs:subClassOf morph:Edema;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "82014009"^^clisko:sct20080731DT].

morph:GrowthAbnormality
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """growth abnormality"""@en;
	rdfs:subClassOf morph:MorphologicallyAbnormalStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "57697001"^^clisko:sct20080731DT].

morph:Neoplasm
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """neoplasm"""@en;
	skos:definition """Abnormal tissue as a result of neoplasia."""@en;
	rdfs:subClassOf morph:GrowthAbnormality, [
		a owl:Restriction; owl:onProperty event:outputOf; owl:someValuesFrom humdis:Neoplasia].

morph:Hypertrophy
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """hypertrophy"""@en;
	rdfs:subClassOf morph:GrowthAbnormality;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "56246009"^^clisko:sct20080731DT].
	
morph:CongestiveHypertrophy
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """congestive hypertrophy"""@en;
	rdfs:subClassOf morph:Hypertrophy;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "7744000"^^clisko:sct20080731DT].

morph:Distortion
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """distortion"""@en;
	skos:definition """Tissue distortion as a result of neoplasia."""@en;
	rdfs:subClassOf morph:GrowthAbnormality.

morph:Inflammation
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:label """inflammation"""@en; # Inflammatory cell infiltration
	rdfs:subClassOf morph:MorphologicallyAbnormalStructure;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "23583003"^^clisko:sct20080731DT].

#
# PROPERTIES
#

morph:hasMorphology
	a owl:ObjectProperty;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalMorphology#>;
	rdfs:domain clinobs:Finding;
	rdfs:range morph:MorphologicallyAbnormalStructure.