@prefix dce: <http://purl.org/dc/elements/1.1/>.
@prefix owl: <http://www.w3.org/2002/07/owl#>.
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#>.
@prefix skos: <http://www.w3.org/2004/02/skos/core#>.
@prefix xsd: <http://www.w3.org/2001/XMLSchema#>.
@prefix quant: <http://eulersharp.sourceforge.net/2003/03swap/quantities#>.
@prefix event: <http://eulersharp.sourceforge.net/2003/03swap/event#>.
@prefix agent: <http://eulersharp.sourceforge.net/2003/03swap/agent#>.
@prefix humanbody: <http://eulersharp.sourceforge.net/2003/03swap/humanBody#>.
@prefix clisko: <http://www.agfa.com/w3c/2009/clinicalSKOSSchemes#>.
@prefix heca: <http://www.agfa.com/w3c/2009/healthCare#>.
@prefix clinobs: <http://www.agfa.com/w3c/2009/clinicalObservation#>.

<http://www.agfa.com/w3c/2009/clinicalObservation>
	a owl:Ontology;
	dce:title """Clinical Observation"""@en;
	dce:creator """Hans Cools, MD; Agfa Healthcare/Belgium"""@en;
	dce:contributor """Until 2010: Pieterjan De Potter; Ghent University - IBBT/ELIS - Multimedia Lab/Belgium"""@en;
	dce:publisher """Agfa Healthcare/Belgium"""@en;
	dce:description """Formal description of general clinical findings, observables, and their relations."""@en;
	dce:format """OWL Full"""@en;
	rdfs:comment """Copyright (c) 2009 Agfa-Gevaert Group / Ghent University - IBBT/ELIS - Multimedia Lab All Rights Reserved THIS IS UNPUBLISHED PROPRIETARY SOURCE CODE OF Agfa-Gevaert Group/ Ghent University - IBBT/ELIS - Multimedia Lab The copyright notice above does not evidence any actual or intended publication of such source code."""@en;
	skos:note """For vital signs see:
		http://www.agfa.com/w3c/2009/bloodPressure#BloodPressure
		http://www.agfa.com/w3c/2009/bodyTemperature#BodyTemperature
		http://www.agfa.com/w3c/2009/pulseRate#PulseRate
		http://www.agfa.com/w3c/2009/respiratoryRate#RespiratoryRate."""@en.

#
# CLASSES
#

clinobs:Finding
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """clinical finding"""@en;
	skos:definition """A manifestation of a patient's health state, e.g. fever."""@en;
	skos:note """Abstracted whether found by patient (often referred to as symptom), health care professional (sign) or someone else."""@en;
	rdfs:subClassOf event:Finding; #, [
		#a owl:Restriction; owl:onProperty agent:hasPlayedRole; owl:someValuesFrom heca:Patient];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "404684003"^^clisko:sct20080731DT].

clinobs:GeneralFinding
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """general clinical finding"""@en;
	skos:definition """A manifestation of a patient's health state involving the whole body."""@en;
	rdfs:subClassOf clinobs:Finding.

clinobs:Observable
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """clinical observable"""@en;
	skos:definition """Something that can be observed in a patient, e.g. body temperature."""@en;
	rdfs:subClassOf event:Observable;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "363787002"^^clisko:sct20080731DT].

# clinobs:PatientState

clinobs:VitalSign
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """vital sign"""@en;
	skos:definition """Sign of life, indicator of a person's general physical condition, to assess the most basic body functions."""@en;
	rdfs:subClassOf clinobs:Observable;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "46680005"^^clisko:sct20080731DT].

clinobs:CardiacRate
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """cardiac rate"""@en;
	skos:definition """Rate of human cardiac pumping as heart beats per unit of time."""@en;
	rdfs:subClassOf quant:Frequency;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "258983007"^^clisko:sct20080731DT].

clinobs:Pain
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """pain"""@en;
	skos:definition """Sensory experience as the unpleasant awareness of a noxious stimulus"""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "22253000"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "A01"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R52.9"^^clisko:icd10DT].

clinobs:RadiatingPain
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """radiating pain"""@en;
	rdfs:subClassOf clinobs:Pain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "301369003"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "L99"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "M54.1"^^clisko:icd10DT].

clinobs:Headache
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """headache"""@en;
	rdfs:subClassOf clinobs:Pain;
	rdfs:subClassOf [
		a owl:Restriction; owl:onProperty clinobs:hasSite; owl:minCardinality """1"""^^xsd:nonNegativeInteger];
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "25064002"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "N01"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R51"^^clisko:icd10DT].

clinobs:NeckPain
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """neck pain"""@en;
	rdfs:subClassOf clinobs:Pain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "81680005"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "L01"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "M54.2"^^clisko:icd10DT].

clinobs:PainInHeadAndNeckRegion
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """pain of head and neck region"""@en;
	rdfs:subClassOf clinobs:Pain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "301365009"^^clisko:sct20080731DT].

clinobs:ChestPain
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """chest pain"""@en;
	rdfs:subClassOf clinobs:Pain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "29857009"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "A11"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R07.4"^^clisko:icd10DT].

clinobs:LeftSidedChestPain
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """left sided chest pain"""@en;
	rdfs:subClassOf clinobs:ChestPain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "285385002"^^clisko:sct20080731DT].

clinobs:PainRadiatingToLeftArm
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """pain radiating to left arm"""@en;
	rdfs:subClassOf clinobs:RadiatingPain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "425677008"^^clisko:sct20080731DT].

clinobs:PainRadiatingToCentreOfChest
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """pain radiating to centre of chest"""@en;
	rdfs:subClassOf clinobs:RadiatingPain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "427365005"^^clisko:sct20080731DT].

clinobs:PainRadiatingToHead
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """pain radiating to head"""@en;
	rdfs:subClassOf clinobs:RadiatingPain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "425839000"^^clisko:sct20080731DT].

clinobs:PainRadiatingToJaw
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """pain radiating to jaw"""@en;
	rdfs:subClassOf clinobs:RadiatingPain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "426555006"^^clisko:sct20080731DT].

clinobs:PainRadiatingToLeftSideOfChest
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """pain radiating to left side of chest"""@en;
	rdfs:subClassOf clinobs:RadiatingPain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "427293006"^^clisko:sct20080731DT].

clinobs:PainRadiatingToUpperAbdomen
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """pain radiating to upper abdomen"""@en;
	rdfs:subClassOf clinobs:RadiatingPain;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "427075000"^^clisko:sct20080731DT].

# SuprapubicPain
# FlankPain
# CostovertebranAngleTenderness

clinobs:Stiffness
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """stiffness"""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "271587009"^^clisko:sct20080731DT].

clinobs:NeckStiffness
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """neck stiffness"""@en;
	rdfs:subClassOf clinobs:Stiffness;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "161882006"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "L01"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "M54.2"^^clisko:icd10DT].

clinobs:Syncope
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """syncope"""@en;
	skos:definition """Brief loss of consciousness caused by transient cerebral ischemia"""@en;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "271594007"^^clisko:sct20080731DT].

clinobs:Dyspnoea
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """dyspnoea"""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "267036007"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "R02"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R06.0"^^clisko:icd10DT].

clinobs:DyspnoeaAtRest
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """dyspnoea at rest"""@en;
	rdfs:subClassOf clinobs:Dyspnoea;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "161941007"^^clisko:sct20080731DT].

clinobs:DyspnoeaOnExertion
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """dyspnoea on exertion"""@en;
	rdfs:subClassOf clinobs:Dyspnoea;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "60845006"^^clisko:sct20080731DT].

clinobs:Tachypnoea
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """tachypnoea"""@en;
	skos:definition """Increased respiration rate, rapid breathing."""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "271823003"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "R02"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R06.0"^^clisko:icd10DT].

clinobs:Fatigue
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """fatigue"""@en;
	rdfs:subClassOf clinobs:GeneralFinding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "84229001"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2;	skos:notation "A04"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R53"^^clisko:icd10DT].

clinobs:WeightLoss
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """weight loss"""@en;
	skos:definition """"Reduction of total body mass, due to a loss of fluid, body fat or adipose tissue and/or lean mass, namely bone mineral deposits, muscle, tendon and other connective tissue."""@en;
	rdfs:subClassOf clinobs:GeneralFinding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "267024001"^^clisko:sct20080731DT].

# "267024001"^^clisko:sct20080731DT, abnormal weight loss
# "309257005"^^clisko:sct20080731DT, excessive weight loss

clinobs:Fever
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """fever"""@en;
	skos:definition """Increase in internal body temperature above normal due to temporary elevation in the body's thermoregulatory set-point."""@en;
	rdfs:subClassOf clinobs:GeneralFinding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "386661006"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "A03"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R50.9"^^clisko:icd10DT].

clinobs:SleepHyperhidrosis
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """sleep hyperhidrosis"""@en;
	rdfs:subClassOf clinobs:GeneralFinding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "42984000"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R61.9"^^clisko:icd10DT].

clinobs:SwollenAnkle
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """swollen ankle"""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "267039000"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "L16"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "M25.4"^^clisko:icd10DT].

clinobs:Oedema
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """oedema"""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "267038008"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "K07"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R60.9"^^clisko:icd10DT].	

clinobs:AnkleOedema
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """ankle oedema"""@en;
	rdfs:subClassOf clinobs:Oedema;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "26237000"^^clisko:sct20080731DT].

clinobs:Palpitations
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """palpitations"""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "80313002"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "K04"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R00.2"^^clisko:icd10DT].

clinobs:RespiratoryCrackles
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """respiratory crackles"""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "48409008"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "R29"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R09.8"^^clisko:icd10DT].

# Nausea

clinobs:Vomiting
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """vomiting"""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "300359004"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "D10"^^clisko:icpc2DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R11"^^clisko:icd10DT].

clinobs:Rash
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """rash"""@en;
	skos:definition """Change of skin appearance (e.g. eruption), color, and/or texture."""@en;
	rdfs:subClassOf clinobs:Finding;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "271807003"^^clisko:sct20080731DT], [
		a skos:Concept; skos:inScheme clisko:icd10; skos:notation "R21"^^clisko:icd10DT].

clinobs:LocalizedRash
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """localized rash"""@en;
	rdfs:subClassOf clinobs:Rash;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "S06"^^clisko:icpc2DT].

clinobs:GeneralizedRash
	a rdfs:Class;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """generalized rash"""@en;
	rdfs:subClassOf clinobs:Rash;
	skos:exactMatch [
		a skos:Concept; skos:inScheme clisko:icpc2; skos:notation "S07"^^clisko:icpc2DT].

# Nasopharyngeal carriage of Neisseria meningitidis

#
# PROPERTIES
#

clinobs:hasObservable
	a owl:ObjectProperty;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """has clinical observable"""@en;
	skos:definition """Specifying an observable of a human patient."""@en;
	rdfs:domain [a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient];
	rdfs:range clinobs:Observable.

clinobs:hasSite
	a owl:ObjectProperty;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """has clinical finding site"""@en;
	skos:definition """Specifying a human body site where a manifestation of a patient's health state is found."""@en;
	rdfs:domain clinobs:Finding;
	rdfs:range [
		rdfs:subClassOf humanbody:Structure, [
			skos:exactMatch [
				a skos:Concept; skos:inScheme clisko:sct20080731; skos:notation "363698007"^^clisko:sct20080731DT]]].

clinobs:hasFinding
	a owl:ObjectProperty;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """has clinical finding"""@en;
	skos:definition """Specifying a finding a human patient has."""@en;
	rdfs:subPropertyOf agent:actsIn;
	rdfs:domain [a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient];
	rdfs:range clinobs:Finding.

clinobs:findingOf
	a owl:ObjectProperty;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """clinical finding of"""@en;
	skos:definition """Specifying a human patient having a clinical finding."""@en;
	rdfs:subPropertyOf agent:hasAgent;
	rdfs:domain clinobs:Finding;
	rdfs:range [a owl:Restriction; owl:onProperty agent:playsRole; owl:someValuesFrom heca:Patient].

clinobs:isNotFinding
	a owl:ObjectProperty;
	rdfs:isDefinedBy <http://www.agfa.com/w3c/2009/clinicalObservation#>;
	rdfs:label """is not clinical finding"""@en;
	skos:definition """Specifying a clinical finding not found in a human patient."""@en;
	rdfs:domain clinobs:Finding;
	rdfs:range clinobs:Finding.