The LUMC Clinical Ontology (LCO) provides an ontology for integration of health observational data collected in the LUMC hospital for patient monitoring and research.
free to use,share,modify. modify with attribution [http://creativecommons.org/licenses/by/4.0/].
LUMC Clinical Ontology (LCO)
A related resource that is a version, edition, or adaptation of the described resource.
A is related to B iff there is some relation between A and B.
is related to
hasScale
has scale
has minimal value
has maximal value
Any measurement of the degree to which the presentation of a disease state has caused pain or damage, established one or more lesions or infectious colonies, and/or taken over or interfered with the normal functioning of the body as a whole, or of one or more organs, tissues, cells or subcellular mechanisms of an organism.
disease severity measurement
an identifier for a donor in a biobank.
donor registry identifier
Systematic, objective appraisal of the significance, effectiveness, and impact of activities or condition according to specified objectives and criteria.
evaluation
An ordered reference standard used to measure incremental changes.
scale
A description of the technique for the appraisal of a subject or object.
evaluation method
a role which inheres in an organism or part thereof from which any part including cell, organ or tissue is removed with the intention that the donated part will be placed into another organism and/or cultured in vitro.
donor role
a reference point against which other things can be evaluated or compared.
standard
every thing is an entity.
entity
information content entity is an object that requires some background knowledge or procedure to correctly interpret.
information content entity
an attribute is a characteristic of some entity.
attribute
A version label is a label for a particular form or variation of an earlier or original type.
version label
a subject role is the role of an individual that is the target of the study.
subject role
a medical screening is a medical test or series used to detect or predict the presence of disease in individuals at risk for disease within a defined group, such as a population, family, or workforce
medical screening
a diagnosis is the result of a medical investigation to identify a disorder from its signs and symptoms.
diagnosis
is base for is a relation between a quality and the realizable entity that it is the basis for.
is base for
A medical procedure is a procedure to identify, examine, alleviate or eliminate an undesirable biological disease or disorder.
medical procedure
a core relation that holds between a part and its whole.
part of
a measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure.
measurement unit label
a measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device.
measurement datum
a primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together.
denotes
healthcare facility
the buildings and organizations where healthcare services are provided, e.g. ward.
date
the particular day, month and year an event has happened or will happen.
order
the act of requesting that a person, business, or organization do or supply something.
a planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies.
assay
a plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.
protocol
a material entity that is designed to perform a function in a scientific investigation, but is not a reagent.
device
located in
a relation between two independent continuants, the target and the location, in which the target is entirely within the location.
starts during is a relation between a process and an information content entity that states a point or period of time when the process has to start. X starts_during Y iff: (start(Y) before_or_simultaneous_with start(X)) AND (start(X) before_or_simultaneous_with end(Y)), e.g. the patient sampling starts during what is stated in the order done by the medical doctor.
starts during
an identifier for a patient participating in the Beat-COVID study.
beat-covid identifier
an identifier for a patient in the clinical database.
clinical identifier
an identifier for a sample or set of samples.
sample identifier
an established standard to which the described resource conforms.
conforms to
a point or period of time associated with an event in the lifecycle of the resource.
an unambiguous reference to the resource within a given context.
identifier
a material entity is a physical entity that is spatially extended, exists as a whole at any point in time and has mass.
material entity
quality
a quality is an attribute that is intrinsically associated with its bearer (or its parts), but whose presence/absence and observed/measured value may vary.
process
a process is an entity that is identifiable only through the unfolding of time, has temporal parts, and unless otherwise specified/predicted, cannot be identified from any instant of time in which it exists.
has attribute is a relation that associates a entity with an attribute where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type.
has attribute
is attribute of
is attribute of is a relation that associates an attribute with an entity where an attribute is an intrinsic characteristic such as a quality, capability, disposition, function, or is an externally derived attribute determined from some descriptor (e.g. a quantity, position, label/identifier) either directly or indirectly through generalization of entities of the same type.
a role is a realizable entity that describes behaviours, rights and obligations of an entity in some particular circumstance.
role
an identifier is a label that specifically refers to (identifies) an entity (instance/type).
has participant
has participant is a relation that describes the participation of the object in the (processual) subject.
has quality is a relation between an entity and the quality that it bears.
has unit is a relation between a quantity and the unit it is a multiple of.
has unit
has role
has role is a relation between an entity and a role that it bears.
has output is a relation between a process and an entity, where the entity is present at the end of the process.
has output
has input is a relation between a process and an entity, where the entity is present at the beginning of the process.
has input
has target is a relation between a process and an entity, where the entity is present at the beginning of the process and undergoes a change or transformation in the process.
has target
a relation between a informational entity and its actual value (numeric, date, text, etc).
has value
realizable entity
a realizable entity is an attribute that is exhibited under some condition and is realized in some process.
the role of a patient is realized in medical examination.
is realized in
person
a person is an object that has certain capacities or attributes constituting personhood.
refers to
refers to is a relation between one entity and the entity that it makes reference to.
is identifier for
a relation between an identifier and an entity.
institute is a society or organization having a object or common factor, and is normally applied to those with a scientific, educational, or social objective, e.g. Leiden University Medical Center (LUMC).
institute
patient role
a patient role is the role of an individual that is the recepient of medical care.
an object is an entity that is wholly identifiable at any instant of time during which it exists.
object
measured at is a relation between a measurement value and the time measurement.
measured at
real
real is the quality of an entity that exists in real space and time.
unsupported
unsupported is an existence quality in which there is no evidence to support the existence of the entity in any world (real or hypothetical).
age is the length of time that a person has lived or a thing has existed.
age
sampling
sampling is the act of obtaining a sample, whether through selection, collection or preparation.
sample
a sample is a limited quantity of something (e.g. an individual or set of individuals from a population, or a portion of a substance) to be used for testing, analysis, inspection, investigation, demonstration, or trial use.
positive
positive is an assertional qualifier that expresses the validity or truth of a basic assertion, e.g. in a medical examination the observation is the presence of a trait or phenotype.
negative
negative is an assertional qualifier that expresses the falsity or lack of truth of a basic assertion, e.g. in a medical examination the observation is the absence of a trait or phenotype.
never refers to in none of the occasions.
never
always indicates that the event occurs at all times.
always
is associated with
x is associated with y when x and y are logically or statistically related to one another.
organ
an organ is a collection of tissues joined in structural unit to serve a common function.
a gene is part of a nucleic acid that contains all the necessary elements to encode a functional transcript.
gene
protein
a protein is an organic polymer that is composed of one or more linear polymers of amino acids.
phenotype
a phenotype is an observable characteristic of an individual.
is encoded by
a relation between two objects, in which the first object is produced from the information contained in the second object.
has bioassay type is a relation that associates the output of a property evaluated in a bioassay and the category of bioassay based on the property or process that the assay is interrogating, e.g. ADMET, functional, etc.
has bioassay type
A human-readable name for the subject.
label
was informed by
was informed by is a relation between two processes where one process communicates to another process. Communication is the exchange of an entity by two activities, one activity using the entity generated by the other.